Carsten Schelmbauer
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Explore the profile of Carsten Schelmbauer including associated specialties, affiliations and a list of published articles.
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9
Citations
81
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Recent Articles
1.
Andruszewski D, Uhlfelder D, Desiato G, Regen T, Schelmbauer C, Blanfeld M, et al.
Mol Psychiatry
. 2024 Oct;
PMID: 39384965
Prenatal imprinting to interleukin 17A (IL-17A) triggers behavioral disorders in offspring. However, reported models of maternal immune activation utilizing immunostimulants, lack specificity to elucidate the anatomical compartments of IL-17A's action...
2.
Leite J, Menezes L, Martins E, Rodrigues T, Tavares L, Ebering A, et al.
iScience
. 2023 Oct;
26(11):108134.
PMID: 37867943
AIM2 is an interferon-inducible HIN-200 protein family member and is well-documented for its roles in innate immune responses as a DNA sensor. Recent studies have highlighted AIM2's function on regulatory...
3.
Johann L, Soldati S, Muller K, Lampe J, Marini F, Klein M, et al.
J Clin Invest
. 2023 Oct;
133(24).
PMID: 37856217
A20 is a ubiquitin-modifying protein that negatively regulates NF-κB signaling. Mutations in A20/TNFAIP3 are associated with a variety of autoimmune diseases, including multiple sclerosis (MS). We found that deletion of...
4.
Bednarczyk M, Bolduan V, Haist M, Stege H, Hieber C, Johann L, et al.
Cells
. 2022 Jul;
11(14).
PMID: 35883631
Heterodimeric β2 integrin surface receptors (CD11a-d/CD18) are specifically expressed by leukocytes that contribute to pathogen uptake, cell migration, immunological synapse formation and cell signaling. In humans, the loss of CD18...
5.
Nikolouli E, Elfaki Y, Herppich S, Schelmbauer C, Delacher M, Falk C, et al.
Cell Mol Immunol
. 2020 Jan;
18(1):182-193.
PMID: 31988493
The vast majority of Foxp3 regulatory T cells (Tregs) are generated in the thymus, and several factors, such as cytokines and unique thymic antigen-presenting cells, are known to contribute to...
6.
Mufazalov I, Andruszewski D, Schelmbauer C, Heink S, Blanfeld M, Masri J, et al.
J Immunol
. 2020 Jan;
204(4):747-751.
PMID: 31924653
IL-6 binds to the IL-6R α-chain (IL-6Rα) and signals via the signal transducer gp130. Recently, IL-6 was found to also bind to the cell surface glycoprotein CD5, which would then...
7.
Schluter T, Schelmbauer C, Karram K, Mufazalov I
J Mol Med (Berl)
. 2018 Aug;
96(10):983-992.
PMID: 30109367
The pleiotropic cytokine IL-1 mediates its biological functions via association with the signaling receptor IL-1R1. Despite an apparent simplicity in IL-1 signaling activation, multiple negative regulators have been identified. The...
8.
Mufazalov I, Schelmbauer C, Regen T, Kuschmann J, Wanke F, Gabriel L, et al.
EMBO J
. 2016 Nov;
36(1):102-115.
PMID: 27827809
Interleukin-1 (IL-1) is implicated in numerous pathologies, including multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). However, the exact mechanism by which IL-1 is involved in the generation...
9.
Mufazalov I, Regen T, Schelmbauer C, Kuschmann J, Muratova A, Nikolaev A, et al.
PLoS One
. 2016 Aug;
11(8):e0161505.
PMID: 27551932
Interleukin-1 (IL-1) plays a crucial role in numerous inflammatory diseases via action on its only known signaling IL-1 receptor type 1 (IL-1R1). To investigate the role of IL-1 signaling in...