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Carrie Derkowski

Explore the profile of Carrie Derkowski including associated specialties, affiliations and a list of published articles. Areas
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Citations 344
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Recent Articles
1.
Haritunians T, Jones M, McGovern D, Shih D, Barrett R, Derkowski C, et al.
Gut . 2011 Jan; 60(8):1060-7. PMID: 21257989
Objective: Genome-wide association studies have identified multiple Crohn's disease (CD) susceptibility loci, including association with non-coding intergenic single-nucleotide polymorphisms (SNPs) at 10q21. Design: To fine-map the 10q21 locus, the authors...
2.
McGovern D, Jones M, Taylor K, Marciante K, Yan X, Dubinsky M, et al.
Hum Mol Genet . 2010 Jun; 19(17):3468-76. PMID: 20570966
Genetic variation in both innate and adaptive immune systems is associated with Crohn's disease (CD) susceptibility, but much of the heritability to CD remains unknown. We performed a genome-wide association...
3.
Michelsen K, Thomas L, Taylor K, Yu Q, Mei L, Landers C, et al.
PLoS One . 2009 Mar; 4(3):e4719. PMID: 19262684
Background: The recently identified member of the TNF superfamily TL1A (TNFSF15) increases IFN-gamma production by T cells in peripheral and mucosal CCR9+ T cells. TL1A and its receptor DR3 are...
4.
McGovern D, Rotter J, Mei L, Haritunians T, Landers C, Derkowski C, et al.
Inflamm Bowel Dis . 2009 Feb; 15(6):883-9. PMID: 19235914
Background: The IL23/IL17 pathway is pivotal in the development of chronic mucosal inflammation seen in Crohn's disease (CD). Genetic variants in the IL23R and IL12B have been associated with CD...
5.
Shen C, Landers C, Derkowski C, Elson C, Targan S
Inflamm Bowel Dis . 2008 Oct; 14(12):1641-51. PMID: 18825772
Background: CBir1 is a dominant antigen with a role in innate and adaptive immunity in mouse models of colitis and antibodies to CBir1 are associated with severe human Crohn's disease...
6.
McGovern D, Taylor K, Landers C, Derkowski C, Dutridge D, Dubinsky M, et al.
Inflamm Bowel Dis . 2008 Aug; 15(1):75-83. PMID: 18720471
Background: Despite recent advances the majority of inflammatory bowel disease (IBD) susceptibility 'genes' remain undiscovered. Recent data suggest that autoimmune conditions may 'share' susceptibility loci. Epidemiological evidence indicates an association...