Carolyn J Anderson
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Explore the profile of Carolyn J Anderson including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
2898
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Recent Articles
1.
Reyes-Gonzalez J, Rajkumar H, Lee W, Baidoo K, Edinger R, Diehl G, et al.
Mol Cancer Ther
. 2025 Feb;
PMID: 39911068
Radiopharmaceutical therapy (RPT) is a promising approach to treating solid tumors, but therapeutic advances are impeded by the lack of broadly expressed targets and shared molecular vulnerability across different tumor...
2.
Ho K, Tatum D, Watkinson L, Carmack T, Jia F, Mascioni A, et al.
J Nucl Med
. 2024 Aug;
65(9):1435-1442.
PMID: 39142831
Here we describe an anti-prostate-specific membrane antigen (PSMA) minibody (IAB2MA) conjugated to an octadentate, macrocyclic chelator based on four 1-hydroxypyridin-2-one coordinating units (Lumi804 [L804]) labeled with Zr (PET imaging) and...
3.
Evaluation of a bimodal, matched pair theranostic agent targeting prostate-specific membrane antigen
Lewis M, Schaedler A, Ho K, Golzy M, Mathur A, Pun M, et al.
Nucl Med Biol
. 2024 Jul;
136-137:108938.
PMID: 39032262
Background: Prostate cancer affects 1 in 6 men, and it is the second‑leading cause of cancer-related death in American men. Surgery is one of the main treatment modalities for prostate...
4.
Rachedi N, Tang Y, Tai Y, Zhao J, Chauvet C, Grynblat J, et al.
Cell Metab
. 2024 May;
36(6):1335-1350.e8.
PMID: 38701775
Perivascular collagen deposition by activated fibroblasts promotes vascular stiffening and drives cardiovascular diseases such as pulmonary hypertension (PH). Whether and how vascular fibroblasts rewire their metabolism to sustain collagen biosynthesis...
5.
Pun M, Gallazzi F, Ho K, Watkinson L, Carmack T, Iweha E, et al.
Mol Pharm
. 2024 Apr;
21(6):2960-2969.
PMID: 38680059
Very late antigen-4 (VLA-4) is a transmembrane integrin protein that is highly expressed in aggressive forms of metastatic melanoma. A small-molecule peptidomimetic, LLP2A, was found to have a low pM...
6.
Nisnboym M, Vincze S, Xiong Z, Sneiderman C, Raphael R, Li B, et al.
Cancer Res Commun
. 2023 Jul;
3(7):1173-1188.
PMID: 37426447
Significance: Immunotherapy may hold promise for the treatment of some patients with GBM. There is a need to assess therapy responsiveness to allow the continuation of effective treatment in responders...
7.
Zhu Q, Barnes C, Mannes P, Latoche J, Day K, Nedrow J, et al.
EJNMMI Res
. 2023 Jun;
13(1):55.
PMID: 37273103
Background: The lack of noninvasive methods for assessment of dysregulated inflammation as a major driver of fibrosis (i.e., inflammation-fibrosis axis) has been a major challenge to precision management of fibrotic...
8.
Mannes P, Barnes C, Biermann J, Latoche J, Day K, Zhu Q, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(3):e2216458120.
PMID: 36626557
The lack of techniques for noninvasive imaging of inflammation has challenged precision medicine management of acute respiratory distress syndrome (ARDS). Here, we determined the potential of positron emission tomography (PET)...
9.
Bellavia M, Patel R, Anderson C
J Nucl Med
. 2022 Oct;
63(11):1636-1641.
PMID: 36215570
Immune checkpoint inhibitors (ICIs) have revolutionized cancer care, but many patients with poorly immunogenic tumors fail to benefit. Preclinical studies have shown that external beam radiotherapy (EBRT) can synergize with...
10.
Olatunji F, Pun M, Herman J, Romero O, Maniatopoulos M, Latoche J, et al.
Mol Cancer Ther
. 2022 Aug;
21(11):1701-1709.
PMID: 35999662
New targeted chemotherapeutics are urgently needed to minimize off-target toxicity and reduce the high-mortality rate associated with metastatic prostate cancer. Herein, we report on the modular synthesis, pharmacokinetics, and efficacy...