Carolyn A Larabell
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Explore the profile of Carolyn A Larabell including associated specialties, affiliations and a list of published articles.
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54
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1773
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Recent Articles
1.
Tervonen A, Leclerc S, Ruokolainen V, Tieu K, Lyonnais S, Niskanen H, et al.
bioRxiv
. 2025 Jan;
PMID: 39803437
Mechanical properties of the nucleus are remodeled not only by extracellular forces transmitted to the nucleus but also by internal modifications, such as those induced by viral infections. During herpes...
2.
Hueschen C, Segev-Zarko L, Chen J, LeGros M, Larabell C, Boothroyd J, et al.
Nat Phys
. 2024 Dec;
20(12):1989-1996.
PMID: 39669527
During host infection, and related unicellular parasites move using gliding, which differs fundamentally from other known mechanisms of eukaryotic cell motility. Gliding is thought to be powered by a thin...
3.
Leclerc S, Gupta A, Ruokolainen V, Chen J, Kunnas K, Ekman A, et al.
PLoS Pathog
. 2024 Apr;
20(4):e1011829.
PMID: 38620036
Viruses target mitochondria to promote their replication, and infection-induced stress during the progression of infection leads to the regulation of antiviral defenses and mitochondrial metabolism which are opposed by counteracting...
4.
Chen J, Vanslembrouck B, Ekman A, Aho V, Larabell C, Le Gros M, et al.
Viruses
. 2022 Dec;
14(12).
PMID: 36560654
Upon infection, viruses hijack the cell machinery and remodel host cell structures to utilize them for viral proliferation. Since viruses are about a thousand times smaller than their host cells,...
5.
Loconte V, Chen J, Vanslembrouck B, Ekman A, McDermott G, Le Gros M, et al.
FASEB J
. 2022 Dec;
37(1):e22681.
PMID: 36519968
Developing in silico models that accurately reflect a whole, functional cell is an ongoing challenge in biology. Current efforts bring together mathematical models, probabilistic models, visual representations, and data to...
6.
Chen J, Vanslembrouck B, Loconte V, Ekman A, Cortese M, Bartenschlager R, et al.
STAR Protoc
. 2022 Feb;
3(1):101176.
PMID: 35199039
The protocol describes step-by-step sample preparation, data acquisition, and segmentation of cellular organelles with soft X-ray tomography. It is designed for microscopes built to perform full-rotation data acquisition on specimens...
7.
Loconte V, Singla J, Li A, Chen J, Ekman A, McDermott G, et al.
Structure
. 2022 Feb;
30(4):510-521.e3.
PMID: 35148829
Inter-organelle interactions are a vital part of normal cellular function; however, these have proven difficult to quantify due to the range of scales encountered in cell biology and the throughput...
8.
Ma J, Do M, Le Gros M, Peskin C, Larabell C, Mori Y, et al.
PLoS Comput Biol
. 2020 Nov;
16(11):e1008356.
PMID: 33196636
For a chemical signal to propagate across a cell, it must navigate a tortuous environment involving a variety of organelle barriers. In this work we study mathematical models for a...
9.
Remesh S, Verma S, Chen J, Ekman A, Larabell C, Adhya S, et al.
Nat Commun
. 2020 Jun;
11(1):2905.
PMID: 32518228
Bacterial nucleoid remodeling dependent on conserved histone-like protein, HU is one of the determining factors in global gene regulation. By imaging of near-native, unlabeled E. coli cells by soft X-ray...
10.
Weinhardt V, Chen J, Ekman A, Guo J, Remesh S, Hammel M, et al.
PLoS One
. 2020 Jan;
15(1):e0227601.
PMID: 31978064
The diversity of living cells, in both size and internal complexity, calls for imaging methods with adaptable spatial resolution. Soft x-ray tomography (SXT) is a three-dimensional imaging technique ideally suited...