Caroline Hick
Overview
Explore the profile of Caroline Hick including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
143
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0
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Recent Articles
1.
Yuliantie E, Nh Trinh P, Hick C, Ebenhoch R, Nar H, Weichert D, et al.
Biochem Pharmacol
. 2024 Aug;
229:116483.
PMID: 39147328
Class B1 G protein-coupled receptors (GPCRs) are peptide hormone receptors and well validated therapeutic targets, however development of non-peptide drugs targeting this class of receptors is challenging. Recently, a series...
2.
Walunj S, Dias M, Kaur C, Wagstaff K, Dey V, Hick C, et al.
Cells
. 2022 Apr;
11(7).
PMID: 35406765
The global burden of malaria and toxoplasmosis has been limited by the use of efficacious anti-parasitic agents, however, emerging resistance in species and threatens disease control worldwide, implying that new...
3.
Ostrovskaya A, Hick C, Hutchinson D, Stringer B, Wookey P, Wootten D, et al.
BMC Cancer
. 2019 Feb;
19(1):157.
PMID: 30777055
Background: Glioblastoma (GBM) is the most common and aggressive type of primary brain cancer. With median survival of less than 15 months, identification and validation of new GBM therapeutic targets...
4.
Dal Maso E, Just R, Hick C, Christopoulos A, Sexton P, Wootten D, et al.
Biochem Pharmacol
. 2017 Dec;
148:111-129.
PMID: 29277692
The calcitonin receptor (CTR) is a class B G protein-coupled receptor that is a therapeutic target for the treatment of hypercalcaemia of malignancy, Paget's disease and osteoporosis. In primates, the...
5.
Koole C, Reynolds C, Mobarec J, Hick C, Sexton P, Sakmar T
J Biol Chem
. 2017 Mar;
292(17):7131-7144.
PMID: 28283573
The glucagon-like peptide-1 receptor (GLP-1R) is a key therapeutic target in the management of type II diabetes mellitus, with actions including regulation of insulin biosynthesis and secretion, promotion of satiety,...
6.
Fraser J, Watanabe S, Wang C, Chan W, Maher B, Lopez-Denman A, et al.
J Infect Dis
. 2014 Jun;
210(11):1780-91.
PMID: 24903662
Background: Dengue virus (DENV) is estimated to cause 390 million infections each year, but there is no licensed vaccine or therapeutic currently available. Methods: We describe a novel, high-throughput screen...
7.
Bartlett R, Hick C, Houston A, Gardiner L, Wallace D
Dementia (London)
. 2013 Dec;
14(6):788-99.
PMID: 24339124
Although attention is paid to involving people with dementia as collaborators in research, the issue of place - where involvement actually occurs - has been neglected. This is significant because...
8.
Dekker L, Daniels Z, Hick C, Elsegood K, Bowden S, Szestak T, et al.
Eur J Pharmacol
. 2005 Dec;
528(1-3):52-8.
PMID: 16325806
The tetrodotoxin-resistant voltage-gated sodium channel alpha-subunit Nav1.8 is expressed in nociceptors and has been implicated in chronic pain. Difficulties of heterologous expression have so far precluded analysis of the pharmacological...
9.
John V, Main M, Powell A, Gladwell Z, Hick C, Sidhu H, et al.
Neuropharmacology
. 2004 Feb;
46(3):425-38.
PMID: 14975698
The voltage-gated sodium channel NaV1.8 (SNS, PN3) is thought to be a molecular correlate of the dorsal root ganglion (DRG) tetrodotoxin resistant (TTX-R) Na+ current. TTX-R/NaV1.8 is an attractive therapeutic...