Caroline G Shimoura
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Explore the profile of Caroline G Shimoura including associated specialties, affiliations and a list of published articles.
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12
Citations
46
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Recent Articles
1.
Shimoura C, Oliveira T, Lincevicius G, Crajoinas R, Oliveira-Sales E, Varela V, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000071
The Goldblatt model of hypertension (2K-1C) in rats is characterized by renal sympathetic nerve activity (rSNA). We investigated the effects of unilateral renal denervation of the clipped kidney (DNX) on...
2.
Shimoura C, Wallace K, Mathis K
Front Med (Lausanne)
. 2023 Jan;
9:1100487.
PMID: 36687431
No abstract available.
3.
Chaudhari S, DSouza B, Morales J, Young-Stubbs C, Shimoura C, Ma R, et al.
Am J Physiol Heart Circ Physiol
. 2022 Nov;
323(6):H1331-H1342.
PMID: 36367687
Hypertension is prevalent in patients with systemic lupus erythematosus (SLE). The goal of the current study is to track the pathogenesis of hypertension and renal injury in SLE, identify contributory...
4.
Chaudhari S, Pham G, Brooks C, Dinh V, Young-Stubbs C, Shimoura C, et al.
Front Physiol
. 2022 Jun;
13:886779.
PMID: 35770194
Despite extensive research and a plethora of therapeutic options, hypertension continues to be a global burden. Understanding of the pathological roles of known and underexplored cellular and molecular pathways in...
5.
Mourao A, Shimoura C, Andrade M, Truong T, Pedrino G, Toney G
Am J Physiol Heart Circ Physiol
. 2021 Aug;
321(3):H580-H591.
PMID: 34355986
Tumor necrosis factor-α (TNFα) in the hypothalamic paraventricular nucleus (PVN) contributes to increased sympathetic nerve activity (SNA) in cardiovascular disease models, but mechanisms are incompletely understood. As previously reported, bilateral...
6.
Morales J, Young-Stubbs C, Shimoura C, Kem W, Uteshev V, Mathis K
Front Med (Lausanne)
. 2021 Apr;
8:642960.
PMID: 33928103
There is a critical need for safe treatment options to control inflammation in patients with systemic lupus erythematosus (SLE) since the inflammation contributes to morbidity and mortality in advanced disease....
7.
Shimoura C, Andrade M, Toney G
J Appl Physiol (1985)
. 2020 Apr;
128(5):1329-1337.
PMID: 32240022
Acute intermittent hypoxia (AIH) triggers sympathetic long-term facilitation (sLTF), a progressive increase in sympathetic nerve activity (SNA) linked to central AT1 receptor (AT1R) activation by circulating angiotensin II (ANG II)....
8.
9.
Varela V, Oliveira-Sales E, Maquigussa E, Borges F, Gattai P, Novaes A, et al.
Kidney Blood Press Res
. 2019 Nov;
44(6):1404-1415.
PMID: 31671420
Background: Mesenchymal stem cells (MSC) improve renal function and renovascular hypertension in the 2-kidney 1-clip model (2K-1C). While MSC play an immunomodulatory role, induce neoangiogenesis, and reduce fibrosis, they do...
10.
Lincevicius G, Shimoura C, Nishi E, Oliveira T, Cespedes J, Bergamaschi C, et al.
Auton Neurosci
. 2017 Jul;
208:43-50.
PMID: 28688830
Sympathetic vasomotor activity is significantly increased in renovascular hypertension. Renal denervation (DnX) has emerged as a novel therapy for resistant hypertension to drug therapy. However, the underlying mechanisms regarding the...