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Caroline Daneault

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Citations 517
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Recent Articles
1.
Rioux J, Boucher G, Forest A, Bouchard B, Coderre L, Daneault C, et al.
medRxiv . 2024 Oct; PMID: 39371119
The inflammatory bowel diseases (IBD) known as Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the gastrointestinal tract believed to arise because of an imbalance between...
2.
Manceau R, Majeur D, Cherian C, Miller C, Wat L, Fisher J, et al.
bioRxiv . 2024 Sep; PMID: 39345476
Lipids are essential for neuron development and physiology. Yet, the central hubs that coordinate lipid supply and demand in neurons remain unclear. Here, we combine invertebrate and vertebrate models to...
3.
Robb J, Boisjoly F, Machuca-Parra A, Coursan A, Manceau R, Majeur D, et al.
Brain Behav Immun . 2024 Sep; 123:315-333. PMID: 39326768
Lipid droplets (LD) are triglyceride storing organelles that have emerged as an important component of cellular inflammatory responses. LD lipolysis via adipose triglyceride lipase (ATGL), the enzyme that catalyses the...
4.
Burelle C, Clapatiuc V, Deschenes S, Cuillerier A, De Loof M, Higgins M, et al.
Commun Biol . 2024 Mar; 7(1):356. PMID: 38519536
Lean patients with NAFLD may develop cardiac complications independently of pre-existent metabolic disruptions and comorbidities. To address the underlying mechanisms independent of the development of obesity, we used a murine...
5.
Yamashita A, Ignatenko O, Nguyen M, Lambert R, Watt K, Daneault C, et al.
Biol Direct . 2023 Sep; 18(1):60. PMID: 37736739
Peroxisomes play a central role in tuning metabolic and signaling programs in a tissue- and cell-type-specific manner. However, the mechanisms by which the status of peroxisomes is communicated and integrated...
6.
Lefort B, Gelinas R, Forest A, Bouchard B, Daneault C, Frayne I, et al.
Biochim Biophys Acta Mol Basis Dis . 2023 Aug; 1869(8):166843. PMID: 37558007
Very-long chain acyl-CoA dehydrogenase (VLCAD) catalyzes the initial step of mitochondrial long chain (LC) fatty acid β-oxidation (FAO). Inherited VLCAD deficiency (VLCADD) predisposes to neonatal arrhythmias whose pathophysiology is still...
7.
Hata M, Andriessen E, Hata M, Diaz-Marin R, Fournier F, Crespo-Garcia S, et al.
Science . 2023 Jan; 379(6627):45-62. PMID: 36603072
Age-related macular degeneration is a prevalent neuroinflammatory condition and a major cause of blindness driven by genetic and environmental factors such as obesity. In diseases of aging, modifiable factors can...
8.
Amro J, Black C, Jemouai Z, Rooney N, Daneault C, Zeytuni N, et al.
Structure . 2022 Dec; 31(4):375-384.e4. PMID: 36513067
Agrobacterium tumefaciens is a natural genetic engineer that transfers DNA into plants, which is the most applied process for generation of genetically modified plants. DNA transfer is mediated by a...
9.
Cuillerier A, Ruiz M, Daneault C, Forest A, Rossi J, Vasam G, et al.
Commun Biol . 2021 Aug; 4(1):989. PMID: 34413467
Mouse models of genetic mitochondrial disorders are generally used to understand specific molecular defects and their biochemical consequences, but rarely to map compensatory changes allowing survival. Here we took advantage...
10.
Botta A, Forest A, Daneault C, Pantopoulos K, Tantiworawit A, Phrommintikul A, et al.
Metabolites . 2021 Feb; 11(2). PMID: 33530524
Despite advances in our knowledge and attempts to improve therapies, β-thalassemia remains a prevalent disorder with increased risk for the development of cardiomyopathy. Using an untargeted discovery-based lipidomic workflow, we...