Carolina Gomis-Perez
Overview
Explore the profile of Carolina Gomis-Perez including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
270
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Nav1.8 in small dorsal root ganglion neurons contributes to vincristine-induced mechanical allodynia
Nascimento de Lima A, Zhang H, Chen L, Effraim P, Gomis-Perez C, Cheng X, et al.
Brain
. 2024 Mar;
147(9):3157-3170.
PMID: 38447953
Vincristine-induced peripheral neuropathy is a common side effect of vincristine treatment, which is accompanied by pain and can be dose-limiting. The molecular mechanisms that underlie vincristine-induced pain are not well...
2.
Urrutia J, Aguado A, Gomis-Perez C, Muguruza-Montero A, Ballesteros O, Zhang J, et al.
BMC Biol
. 2021 May;
19(1):109.
PMID: 34020651
Background: The amino acid sequence of proteins generally carries all the necessary information for acquisition of native conformations, but the vectorial nature of translation can additionally determine the folding outcome....
3.
Sizova D, Huang J, Akin E, Estacion M, Gomis-Perez C, Waxman S, et al.
J Biol Chem
. 2019 Dec;
295(4):1077-1090.
PMID: 31822564
Genetic and functional studies have confirmed an important role for the voltage-gated sodium channel Nav1.9 in human pain disorders. However, low functional expression of Nav1.9 in heterologous systems ( in...
4.
Gomis-Perez C, Urrutia J, Marce-Grau A, Malo C, Lopez-Laso E, Felipe-Rucian A, et al.
Epilepsia
. 2018 Nov;
60(1):139-148.
PMID: 30478917
Objective: To gain insight into the mechanisms underlying KCNQ2 encephalopathy by examining the electrophysiologic properties of mutant Kv7.2 channels in different multimeric configurations. Methods: We analyzed the genotype-phenotype relationship in...
5.
Mis M, Yang Y, Tanaka B, Gomis-Perez C, Liu S, Dib-Hajj F, et al.
J Neurosci
. 2018 Nov;
39(3):382-392.
PMID: 30459225
Pain is a complex process that involves both detection in the peripheral nervous system and perception in the CNS. Individual-to-individual differences in pain are well documented, but not well understood....
6.
Alaimo A, Etxeberria A, Gomez-Posada J, Gomis-Perez C, Fernandez-Orth J, Malo C, et al.
Channels (Austin)
. 2018 Aug;
12(1):299-310.
PMID: 30126342
Heteromers of Kv7.2/Kv7.3 subunits constitute the main substrate of the neuronal M-current that limits neuronal hyper-excitability and firing frequency. Calmodulin (CaM) binding is essential for surface expression of Kv7 channels,...
7.
Bernardo-Seisdedos G, Nunez E, Gomis-Perez C, Malo C, Villarroel A, Millet O
Proc Natl Acad Sci U S A
. 2018 Feb;
115(10):2395-2400.
PMID: 29463698
The Kv7.2 (KCNQ2) channel is the principal molecular component of the slow voltage-gated, noninactivating K M-current, a key controller of neuronal excitability. To investigate the calmodulin (CaM)-mediated Ca gating of...
8.
Alaimo A, Nunez E, Aivar P, Fernandez-Orth J, Gomis-Perez C, Bernardo-Seisdedos G, et al.
Sci Rep
. 2017 Oct;
7(1):13425.
PMID: 29044210
Tetrameric coiled-coil structures are present in many ion channels, often adjacent to a calmodulin (CaM) binding site, although the relationship between the two is not completely understood. Here we examine...
9.
Gomis-Perez C, Soldovieri M, Malo C, Ambrosino P, Taglialatela M, Areso P, et al.
Front Mol Neurosci
. 2017 May;
10:117.
PMID: 28507506
- Calmodulin-dependent Kv7.2 current density without the need of binding calcium.- Kv7.2 current density increase is accompanied with resistance to PI(4,5)P depletion.- Kv7.3 current density is insensitive to calmodulin elevation.-...
10.
Anta B, Martin-Rodriguez C, Gomis-Perez C, Calvo L, Lopez-Benito S, Calderon-Garcia A, et al.
J Biol Chem
. 2016 Jul;
291(36):19132-45.
PMID: 27445338
Ubiquitination of the TrkA neurotrophin receptor in response to NGF is critical in the regulation of TrkA activation and functions. TrkA is ubiquitinated, among other E3 ubiquitin ligases, by Nedd4-2....