Carolina D Garciarena
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Explore the profile of Carolina D Garciarena including associated specialties, affiliations and a list of published articles.
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24
Citations
395
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Recent Articles
11.
Yeves A, Garciarena C, Nolly M, de Cingolani G, Cingolani H, Ennis I
Hypertension
. 2010 Aug;
56(4):690-5.
PMID: 20713918
The beneficial effect of phosphodiesterase 5A inhibition in ischemia/reperfusion injury and cardiac hypertrophy is well established. Inhibition of the cardiac Na(+)/H(+) exchanger (NHE-1) exerts beneficial effects on these same conditions,...
12.
De Giusti V, Garciarena C, Aiello E
J Mol Cell Cardiol
. 2009 Aug;
47(5):716-22.
PMID: 19646989
The sarcolemmal Na+/HCO3- cotransporter (NBC) plays an important role in intracellular pH (pH(i)) regulation in the heart. In the present work we studied, in isolated cat ventricular myocytes, the role...
13.
Garciarena C, Pinilla O, Nolly M, Laguens R, Escudero E, Cingolani H, et al.
Hypertension
. 2009 Feb;
53(4):708-14.
PMID: 19221208
The effect of endurance training (swimming 90 min/d for 5 days a week for 60 days) on cardiac hypertrophy was investigated in the spontaneously hypertensive rat (SHR). Sedentary SHRs (SHR-Cs)...
14.
Garciarena C, Caldiz C, Portiansky E, de Cingolani G, Ennis I
J Appl Physiol (1985)
. 2009 Jan;
106(4):1325-31.
PMID: 19179646
Na(+)/H(+) exchanger (NHE-1) inhibition was demonstrated to induce the regression of cardiac hypertrophy (CH) in several experimental models and to inhibit mitochondrial death pathway in "in-vitro" experiments. Since recent reports...
15.
Alvarez M, Caldiz C, Fantinelli J, Garciarena C, Console G, de Cingolani G, et al.
Hypertens Res
. 2008 Oct;
31(7):1465-76.
PMID: 18957818
The aim of this work was to assess the possible correlation between oxidative damage and the development of cardiac hypertrophy in heart tissue from young (40-d-old) and older (4-, 11-...
16.
Garciarena C, Caldiz C, Correa M, Schinella G, Mosca S, de Cingolani G, et al.
J Appl Physiol (1985)
. 2008 Sep;
105(6):1706-13.
PMID: 18801963
The possibility of a direct mitochondrial action of Na(+)/H(+) exchanger-1 (NHE-1) inhibitors decreasing reactive oxygen species (ROS) production was assessed in cat myocardium. Angiotensin II and endothelin-1 induced an NADPH...
17.
Cingolani H, Perez N, Aiello E, Ennis I, Garciarena C, Villa-Abrille M, et al.
Front Biosci
. 2008 May;
13:7096-114.
PMID: 18508719
The enhanced activity of the cardiac Na+/H+ exchanger (NHE-1) after myocardial stretch is considered a key step of the intracellular signaling pathway leading to the slow force response to stretch...
18.
Caldiz C, Garciarena C, Dulce R, Novaretto L, Yeves A, Ennis I, et al.
J Physiol
. 2007 Sep;
584(Pt 3):895-905.
PMID: 17823205
When the length of the myocardium is increased, a biphasic response to stretch occurs involving an initial rapid increase in force followed by a delayed slow increase called the slow...
19.
Ennis I, Garciarena C, Escudero E, Perez N, Dulce R, Camilion de Hurtado M, et al.
Can J Physiol Pharmacol
. 2007 Jul;
85(3-4):301-10.
PMID: 17612638
Na+/H+ exchanger-1 (NHE-1) inhibition induces cardiac hypertrophy regression and (or) prevention in several experimental models, although the intracellular events involved remain unclarified. We aimed to determine whether the calcineurin/NFAT pathway...
20.
Perez N, Piaggio M, Ennis I, Garciarena C, Morales C, Escudero E, et al.
Hypertension
. 2007 Mar;
49(5):1095-103.
PMID: 17339532
Acute phosphodiesterase 5A inhibition by sildenafil or EMD360527/5 promoted profound inhibition of the cardiac Na(+)/H(+) exchanger (NHE-1), detected by the almost null intracellular pH recovery from an acute acid load...