Carole Garofalo
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Explore the profile of Carole Garofalo including associated specialties, affiliations and a list of published articles.
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29
Citations
974
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Recent Articles
1.
Daniel N, Le Barz M, Mitchell P, Varin T, Julien I, Farabos D, et al.
Function (Oxf)
. 2023 Feb;
4(2):zqac069.
PMID: 36778746
We compared endogenous ω-3 PUFA production to supplementation for improving obesity-related metabolic dysfunction. Fat-1 transgenic mice, who endogenously convert exogenous ω-6 to ω-3 PUFA, and wild-type littermates were fed a...
2.
Fang F, Nuyt A, Garofalo C, Zhang J, Julien P, Fraser W, et al.
BMJ Open Diabetes Res Care
. 2021 Mar;
9(1).
PMID: 33687921
Introduction: Oxidized low-density lipoprotein (OxLDL), a biomarker of oxidative stress, itself possesses proatherogenic and proinflammatory effects. Elevated circulating OxLDL levels have been consistently associated with insulin resistance and diabetes in...
3.
Altered proteome of high-density lipoproteins from paediatric acute lymphoblastic leukemia survivors
Fournier M, Bonneil E, Garofalo C, Grimard G, Laverdiere C, Krajinovic M, et al.
Sci Rep
. 2019 Mar;
9(1):4268.
PMID: 30862935
Acute lymphoblastic leukemia (ALL) is the most frequent malignancy in children. With the use of more modern, efficient treatments, 5-year survival has reached more than 90% in this population. However,...
4.
Kleme M, Sane A, Garofalo C, Seidman E, Brochiero E, Berthiaume Y, et al.
Nutrients
. 2018 Jun;
10(7).
PMID: 29954133
Background: Cystic Fibrosis (CF) is a genetic disease in which the intestine exhibits oxidative and inflammatory markers. As mitochondria are the central source and the main target of reactive oxygen...
5.
Yeganeh P, Leahy J, Spahis S, Patey N, Desjardins Y, Roy D, et al.
J Nutr Biochem
. 2018 Apr;
57:56-66.
PMID: 29674247
Inflammatory bowel diseases (IBDs) are multifaceted and relapsing immune disorders, which necessitate long-term dependence on powerful drugs. As the use of natural product-based therapies has emerged as a promising intervention,...
6.
Leahy J, Spahis S, Bonneil E, Garofalo C, Grimard G, Morel S, et al.
Metabolism
. 2018 Mar;
85:151-160.
PMID: 29563052
Background: Childhood acute lymphoblastic leukemia (cALL) is the most prevalent form of cancer in children. Due to advances in treatment and therapy, young cALL subjects now achieve a 90% survival...
7.
Sane A, Seidman E, Peretti N, Kleme M, Delvin E, Deslandres C, et al.
Arterioscler Thromb Vasc Biol
. 2017 Oct;
37(12):2243-2251.
PMID: 28982670
Background: Understanding the specific mechanisms of rare autosomal disorders has greatly expanded insights into the complex processes regulating intestinal fat transport. Sar1B GTPase is one of the critical proteins governing...
8.
Morel S, Leahy J, Fournier M, Lamarche B, Garofalo C, Grimard G, et al.
J Lipid Res
. 2017 Mar;
58(5):982-993.
PMID: 28274961
Survivors of acute lymphoblastic leukemia (ALL), the most common cancer in children, are at increased risk of developing late cardiometabolic conditions. However, the mechanisms are not fully understood. This study...
9.
Denis M, Roy D, Yeganeh P, Desjardins Y, Varin T, Haddad N, et al.
Clin Sci (Lond)
. 2016 Sep;
130(23):2217-2237.
PMID: 27630205
Diets rich in fruits and vegetables may reduce oxidative stress (OxS) and inflammation via several mechanisms. These beneficial effects may be due to their high polyphenol content. The aims of...
10.
Kleme M, Sane A, Garofalo C, Levy E
Int J Biochem Cell Biol
. 2016 Mar;
74:84-94.
PMID: 26923293
Unlabelled: Cystic fibrosis (CF) is a multisystemic pathology caused by mutations of the CF transmembrane conductance regulator (CFTR) gene. Objectives: As the intestine harbors the greatest number of CFTR transcripts...