Carole Dufouil
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Explore the profile of Carole Dufouil including associated specialties, affiliations and a list of published articles.
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174
Citations
11143
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Recent Articles
1.
Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification
DAoust T, Clocchiatti-Tuozzo S, Rivier C, Mishra A, Hachiya T, Grenier-Boley B, et al.
Alzheimers Dement
. 2025 Mar;
21(3):e70014.
PMID: 40042447
Introduction: An integrative polygenic risk score (iPRS) capturing the neurodegenerative and vascular contribution to dementia could identify high-risk individuals and improve risk prediction. Methods: We developed an iPRS for dementia...
2.
Wu Y, Hayes-Larson E, Zhou Y, Bouteloup V, Zimmerman S, Pederson A, et al.
Ann Epidemiol
. 2025 Jan;
102:86-90.
PMID: 39800088
Purpose: Harmonizing variables for constructs measured differently across studies is essential for comparing, combining, and generalizing results. We developed and fielded a brief survey to harmonize Likert and continuous versions...
3.
Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi S, et al.
Mol Psychiatry
. 2024 Dec;
PMID: 39633006
Due to methodological reasons, the X-chromosome has not been featured in the major genome-wide association studies on Alzheimer's Disease (AD). To address this and better characterize the genetic landscape of...
4.
Patel Y, Shin J, Sliz E, Tang A, Mishra A, Xia R, et al.
Nat Commun
. 2024 Nov;
15(1):9517.
PMID: 39496600
White matter hyperintensities index structural abnormalities in the cerebral white matter, including axonal damage. The latter may promote atrophy of the cerebral cortex, a key feature of dementia. Here, we...
5.
Le Scouarnec L, Bouteloup V, van der Veere P, van der Flier W, Teunissen C, Verberk I, et al.
Alzheimers Res Ther
. 2024 Oct;
16(1):219.
PMID: 39394180
Background: The accumulation of amyloid-β (Aβ) peptide in the brain is a hallmark of Alzheimer's disease (AD), occurring years before symptom onset. Current methods for quantifying in vivo amyloid load...
6.
Ahmad S, Imtiaz M, Mishra A, Wang R, Herrera-Rivero M, Bis J, et al.
Commun Biol
. 2024 Sep;
7(1):1103.
PMID: 39251807
Neurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood...
7.
Bercu A, Dufouil C, Debette S, Joliot M, Tsuchida A, Helmer C, et al.
Alzheimers Dement (Amst)
. 2024 May;
16(2):e12578.
PMID: 38800122
Abstract: The utility of brain magnetic resonance imaging (MRI) for predicting dementia is debated. We evaluated the added value of repeated brain MRI, including atrophy and cerebral small vessel disease...
8.
Sargurupremraj M, Soumare A, Bis J, Surakka I, Jurgenson T, Joly P, et al.
JAMA Netw Open
. 2024 May;
7(5):e2412824.
PMID: 38776079
Importance: Vascular disease is a treatable contributor to dementia risk, but the role of specific markers remains unclear, making prevention strategies uncertain. Objective: To investigate the causal association between white...
9.
Grasset L, Bouteloup V, Cacciamani F, Pellegrin I, Planche V, Chene G, et al.
Neurology
. 2024 Apr;
102(9):e209307.
PMID: 38626384
Background And Objectives: Elevated levels of Alzheimer disease (AD) blood-based biomarkers are associated with accelerated cognitive decline. However, their distinct relationships with specific cognitive and functional domains require further investigation....
10.
Bouteloup V, Pellegrin I, Dubois B, Chene G, Planche V, Dufouil C
Neurology
. 2024 Mar;
102(8):e209219.
PMID: 38527237
Background And Objectives: Patients' comorbidities can affect Alzheimer disease (AD) blood biomarker concentrations. Because a limited number of factors have been explored to date, our aim was to assess the...