Carola G Vinuesa
Overview
Explore the profile of Carola G Vinuesa including associated specialties, affiliations and a list of published articles.
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127
Citations
10114
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Recent Articles
1.
Menon S, Maurice D, Robinson L, Milner J, Pascual V, Vinuesa C, et al.
J Clin Immunol
. 2024 Oct;
45(1):27.
PMID: 39433707
No abstract available.
2.
Sestan M, Arsov T, Kifer N, Frkovic M, Grguric D, Ellyard J, et al.
Scand J Immunol
. 2024 Oct;
100(6):e13411.
PMID: 39380326
The purpose of this study was to identify new and low-frequency gene variants using whole exome sequencing (WES) in patients with childhood-onset systemic lupus erythematosus (cSLE), that may be involved...
3.
4.
Medhavy A, Athanasopoulos V, Bassett K, He Y, Stanley M, Enosi Tuipulotu D, et al.
Nat Immunol
. 2024 Jul;
25(9):1678-1691.
PMID: 39060650
Whole-exome sequencing of two unrelated kindreds with systemic autoimmune disease featuring antinuclear antibodies with IgG4 elevation uncovered an identical ultrarare heterozygous TNIP1 variant segregating with disease. Mice with the orthologous...
5.
He Y, Vinuesa C
Adv Immunol
. 2024 Jun;
162:109-133.
PMID: 38866437
Spontaneously formed germinal centers (GCs) have been reported in most mouse models of human autoimmune disease and autoimmune patients, and have long been considered a source of somatically-mutated and thus...
6.
Cardinez C, Hao Y, Kwong K, Davies A, Downes M, Roberts N, et al.
Nat Commun
. 2024 Mar;
15(1):2345.
PMID: 38528069
Loss-of-function mutations have provided crucial insights into the immunoregulatory actions of Foxp3+ regulatory T cells (Tregs). By contrast, we know very little about the consequences of defects that amplify aspects...
7.
Tacho-Pinot R, Vinuesa C
Trends Immunol
. 2024 Mar;
45(4):234-236.
PMID: 38521715
The role of antibody affinity in plasma cell (PC) differentiation from germinal centers (GCs) remains contested. Parallel studies by Sprumont et al. and Sutton and Gao et al. show that...
8.
Qin Y, Ma J, Vinuesa C
Curr Opin Rheumatol
. 2024 Feb;
36(3):191-200.
PMID: 38420886
Purpose Of Review: This review aims to provide an overview of the genes and molecular pathways involved in monogenic lupus, the implications for genome diagnosis, and the potential therapies targeting...
9.
Zhang Y, Morris R, Brown G, Lorenzo A, Meng X, Kershaw N, et al.
J Exp Med
. 2024 Feb;
221(4).
PMID: 38417019
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with a clear genetic component. While most SLE patients carry rare gene variants in lupus risk genes, little is known about...
10.
Dai D, Gu S, Han X, Ding H, Jiang Y, Zhang X, et al.
Science
. 2024 Jan;
383(6681):413-421.
PMID: 38271512
Age-associated B cells (ABCs) accumulate during infection, aging, and autoimmunity, contributing to lupus pathogenesis. In this study, we screened for transcription factors driving ABC formation and found that zinc finger...