Carmen Adriaens
Overview
Explore the profile of Carmen Adriaens including associated specialties, affiliations and a list of published articles.
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10
Citations
1142
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Recent Articles
1.
Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al.
Nat Med
. 2024 Feb;
30(5):1506.
PMID: 38332041
No abstract available.
2.
Bevill S, Casani-Galdon S, El Farran C, Cytrynbaum E, Macias K, Oldeman S, et al.
Cell Genom
. 2023 Jul;
3(7):100321.
PMID: 37492096
Amplification of MDM2 on supernumerary chromosomes is a common mechanism of P53 inactivation across tumors. Here, we investigated the impact of MDM2 overexpression on chromatin, gene expression, and cellular phenotypes...
3.
Nunez J, Chen J, Pommier G, Cogan J, Replogle J, Adriaens C, et al.
Cell
. 2021 Apr;
184(9):2503-2519.e17.
PMID: 33838111
A general approach for heritably altering gene expression has the potential to enable many discovery and therapeutic efforts. Here, we present CRISPRoff-a programmable epigenetic memory writer consisting of a single...
4.
Johnstone S, Reyes A, Qi Y, Adriaens C, Hegazi E, Pelka K, et al.
Cell
. 2020 Aug;
182(6):1474-1489.e23.
PMID: 32841603
Widespread changes to DNA methylation and chromatin are well documented in cancer, but the fate of higher-order chromosomal structure remains obscure. Here we integrated topological maps for colon tumors and...
5.
The long noncoding RNA is seemingly dispensable for normal tissue homeostasis and cancer cell growth
Adriaens C, Rambow F, Bervoets G, Silla T, Mito M, Chiba T, et al.
RNA
. 2019 Sep;
25(12):1681-1695.
PMID: 31551298
is one of the most studied lncRNAs, in part because its silencing in mice causes defects in mammary gland development and corpus luteum formation and protects them from skin cancer...
6.
Adriaens C, Serebryannyy L, Feric M, Schibler A, Meaburn K, Kubben N, et al.
Histochem Cell Biol
. 2018 Sep;
150(6):579-592.
PMID: 30238154
The past decades have provided remarkable insights into how the eukaryotic cell nucleus and the genome within it are organized. The combined use of imaging, biochemistry and molecular biology approaches...
7.
Rambow F, Rogiers A, Marin-Bejar O, Aibar S, Femel J, Dewaele M, et al.
Cell
. 2018 Jul;
174(4):843-855.e19.
PMID: 30017245
Many patients with advanced cancers achieve dramatic responses to a panoply of therapeutics yet retain minimal residual disease (MRD), which ultimately results in relapse. To gain insights into the biology...
8.
9.
Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al.
Nat Med
. 2016 Jul;
22(8):861-8.
PMID: 27376578
In a search for mediators of the p53 tumor suppressor pathway, which induces pleiotropic and often antagonistic cellular responses, we identified the long noncoding RNA (lncRNA) NEAT1. NEAT1 is an...
10.
Standaert L, Adriaens C, Radaelli E, Van Keymeulen A, Blanpain C, Hirose T, et al.
RNA
. 2014 Oct;
20(12):1844-9.
PMID: 25316907
The lncRNA Neat1 is an essential architectural component of paraspeckle nuclear bodies. Although cell-based studies identified Neat1-paraspeckles as key regulators of gene expression through retention of hyperdited mRNAs and/or transcription...