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Carmela Giglione

Explore the profile of Carmela Giglione including associated specialties, affiliations and a list of published articles. Areas
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Articles 86
Citations 2013
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Recent Articles
1.
El Amri C, Giglione C, Lalmanach G
Biochimie . 2024 Oct; 226:1-3. PMID: 39374892
No abstract available.
2.
Brunje A, Fussl M, Eirich J, Boyer J, Heinkow P, Neumann U, et al.
Mol Cell Proteomics . 2024 Sep; 23(11):100850. PMID: 39349166
Protein N-acetylation is one of the most abundant co- and post-translational modifications in eukaryotes, extending its occurrence to chloroplasts within vascular plants. Recently, a novel plastidial enzyme family comprising eight...
3.
Eirich J, Boyer J, Armbruster L, Ivanauskaite A, de la Torre C, Meinnel T, et al.
Mol Cell Proteomics . 2024 Sep; 23(11):100845. PMID: 39321874
Protein acetylation is a key co- and post-translational modification. However, how different types of acetylation respond to environmental stress is still unknown. To address this, we investigated the role of...
4.
Riviere F, Dian C, Dutheil R, Monassa P, Giglione C, Meinnel T
Structure . 2024 Aug; 32(10):1737-1750.e3. PMID: 39208793
N-myristoyltransferases (NMTs) catalyze essential acylations of N-terminal alpha or epsilon amino groups of glycines or lysines. Here, we reveal that peptides tightly fitting the optimal glycine recognition pattern of human...
5.
Guedes J, Boyer J, Elurbide J, Carte B, Redeker V, Sago L, et al.
Mol Cell Biol . 2024 Aug; 44(9):358-371. PMID: 39099191
N-terminal acetyltransferase B (NatB) is a major contributor to the N-terminal acetylome and is implicated in several key cellular processes including apoptosis and proteostasis. However, the molecular mechanisms linking NatB-mediated...
6.
Buggiani J, Meinnel T, Giglione C, Frottin F
Biochimie . 2024 Apr; 226:148-164. PMID: 38642824
The proteostasis network and associated protein quality control (PQC) mechanisms ensure proteome functionality and are essential for cell survival. A distinctive feature of eukaryotic cells is their high degree of...
7.
Wu X, Segall A, Giglione C, Meinnel T
Microbiol Resour Announc . 2024 Feb; 13(4):e0122223. PMID: 38415641
The entire 4.6-Mb genome of sp. 16, encoding 4,270 genes, best matches with . A 46-kb plasmid (pVDT1), alongside two circular chromosomes, showcases / partition genes and three toxin/antitoxin systems...
8.
Gong X, Boyer J, Gierlich S, Pozoga M, Weidenhausen J, Sinning I, et al.
Cell Rep . 2024 Feb; 43(2):113768. PMID: 38363676
The ribosome-tethered N-terminal acetyltransferase A (NatA) acetylates 52% of soluble proteins in Arabidopsis thaliana. This co-translational modification of the N terminus stabilizes diverse cytosolic plant proteins. The evolutionary conserved Huntingtin...
9.
Meinnel T, Boyer J, Giglione C
Methods Mol Biol . 2023 Sep; 2718:137-150. PMID: 37665458
Global acetylation profiling (GAP) consists of heterologous expression of a given N-acetyltransferase (NAT) in Escherichia coli to assess its specificity. The remarkable sensitivity and robustness of the GAP pipeline relies...
10.
Etherington R, Bailey M, Boyer J, Armbruster L, Cao X, Coates J, et al.
Plant Physiol . 2023 Jul; 193(3):2086-2104. PMID: 37427787
The acetylation-dependent (Ac/)N-degron pathway degrades proteins through recognition of their acetylated N-termini (Nt) by E3 ligases called Ac/N-recognins. To date, specific Ac/N-recognins have not been defined in plants. Here we...