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Carlos Manlio Diaz-Garcia

Explore the profile of Carlos Manlio Diaz-Garcia including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 530
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Recent Articles
11.
Diaz-Garcia C, Meyer D, Nathwani N, Rahman M, Martinez-Francois J, Yellen G
Elife . 2021 Feb; 10. PMID: 33555254
When neurons engage in intense periods of activity, the consequent increase in energy demand can be met by the coordinated activation of glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative...
12.
Koveal D, Diaz-Garcia C, Yellen G
Curr Opin Neurobiol . 2020 Jun; 63:111-121. PMID: 32559637
Over the past decade, genetically encoded fluorescent biosensors that report metabolic changes have become valuable tools for understanding brain metabolism. These sensors have been targeted to specific brain regions and...
13.
Diaz-Garcia C, Lahmann C, Martinez-Francois J, Li B, Koveal D, Nathwani N, et al.
J Neurosci Res . 2019 May; 97(8):946-960. PMID: 31106909
Glucose is an essential source of energy for the brain. Recently, the development of genetically encoded fluorescent biosensors has allowed real time visualization of glucose dynamics from individual neurons and...
14.
Diaz-Garcia C, Yellen G
J Neurosci Res . 2018 Dec; 97(8):883-889. PMID: 30575090
Brain metabolism increases during stimulation, but this increase does not affect all energy metabolism equally. Briefly after stimulation, there is a local increase in cerebral blood flow and in glucose...
15.
Garcia-Delgado N, Velasco M, Sanchez-Soto C, Diaz-Garcia C, Hiriart M
Front Endocrinol (Lausanne) . 2018 Mar; 9:40. PMID: 29556214
Pancreatic beta cells during the first month of development acquire functional maturity, allowing them to respond to variations in extracellular glucose concentration by secreting insulin. Changes in ionic channel activity...
16.
Velasco M, Larque C, Diaz-Garcia C, Sanchez-Soto C, Hiriart M
Methods Mol Biol . 2017 Dec; 1727:261-273. PMID: 29222788
In this chapter, we describe the methods used to culture mainly rat pancreatic beta cells. We consider necessary to use this approach to get more information about physiological, biophysical, and...
17.
Carbajal-Ramirez A, Garcia-Macedo R, Diaz-Garcia C, Sanchez-Soto C, Padron A, Escobedo DE LA Pena J, et al.
BMC Neurol . 2017 Aug; 17(1):161. PMID: 28841856
Background: Neuropathy is one of the major complications of type 2 diabetes mellitus. Our first aim was to determine the clinical characteristics of a population of diabetic patients with different...
18.
Diaz-Garcia C, Mongeon R, Lahmann C, Koveal D, Zucker H, Yellen G
Cell Metab . 2017 Aug; 26(2):361-374.e4. PMID: 28768175
Proper brain function requires a substantial energy supply, up to 20% of whole-body energy in humans, and brain activation produces large dynamic variations in energy demand. While local increases in...
19.
Velasco M, Diaz-Garcia C, Larque C, Hiriart M
Mol Pharmacol . 2016 Jul; 90(3):341-57. PMID: 27436126
Pancreatic beta cells, unique cells that secrete insulin in response to an increase in glucose levels, play a significant role in glucose homeostasis. Glucose-stimulated insulin secretion (GSIS) in pancreatic beta...
20.
Diaz-Garcia C, Aguero-Chapin G, Antunes A, Vasconcelos V
Curr Top Med Chem . 2015 Feb; 15(7):580. PMID: 25686736
No abstract available.