Carlos E Pedraza
Overview
Explore the profile of Carlos E Pedraza including associated specialties, affiliations and a list of published articles.
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10
Citations
291
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Recent Articles
1.
Jagielska A, Radzwill K, Espinosa-Hoyos D, Yang M, Kowsari K, Farley J, et al.
Sci Rep
. 2023 Nov;
13(1):19529.
PMID: 37945646
Multiple sclerosis (MS), a chronic neurodegenerative disease driven by damage to the protective myelin sheath, is currently incurable. Today, all clinically available treatments modulate the immune-mediated symptoms of the disease...
2.
Cao J, Hu Y, Shazeeb M, Pedraza C, Pande N, Weinstock D, et al.
ASN Neuro
. 2018 May;
10:1759091418777329.
PMID: 29806482
The compact myelin sheath is important for axonal function, and its loss can lead to neuronal cell death and irreversible functional deficits. Myelin is vulnerable to a variety of metabolic,...
3.
Li Y, Dunphy J, Pedraza C, Lynch C, Cardona S, Macklin W, et al.
J Virol
. 2016 Jan;
90(7):3385-99.
PMID: 26764005
Unlabelled: Certain murine leukemia viruses (MLVs) are capable of inducing fatal progressive spongiform motor neuron disease in mice that is largely mediated by viral Env glycoprotein expression within central nervous...
4.
Pedraza C, Taylor C, Pereira A, Seng M, Tham C, Izrael M, et al.
ASN Neuro
. 2014 Oct;
6(4).
PMID: 25289646
In inflammatory demyelinating diseases such as multiple sclerosis (MS), myelin degradation results in loss of axonal function and eventual axonal degeneration. Differentiation of resident oligodendrocyte precursor cells (OPCs) leading to...
5.
Pedraza C, Monk R, Lei J, Hao Q, Macklin W
Glia
. 2008 May;
56(12):1339-52.
PMID: 18512250
Much current knowledge of oligodendrocyte biology, the myelin-forming cells in the central nervous system, comes from cell culture studies mainly from postnatal rat tissue but mouse cells have been much...
6.
Dy P, Penzo-Mendez A, Wang H, Pedraza C, Macklin W, Lefebvre V
Nucleic Acids Res
. 2008 Apr;
36(9):3101-17.
PMID: 18403418
The group C of Sry-related high-mobility group (HMG) box (Sox) transcription factors has three members in most vertebrates: Sox4, Sox11 and Sox12. Sox4 and Sox11 have key roles in cardiac,...
7.
Pedraza C, Podlesniy P, Vidal N, Arevalo J, Lee R, Hempstead B, et al.
Am J Pathol
. 2005 Feb;
166(2):533-43.
PMID: 15681836
The pro-form of nerve growth factor (pro-NGF) has been shown to be a high affinity ligand for p75NTR and to induce apoptosis through this receptor. It has been reported that...
8.
Navarra M, Baltrons M, Sardon T, Pedraza C, Garcia A
Neurochem Int
. 2004 Aug;
45(6):937-46.
PMID: 15312988
The human immunodeficiency virus type-1 (HIV-1) coat glycoprotein gp120 has been proposed as a likely etiologic agent of HIV-associated dementia (HAD). The pathogenic mechanisms underlying HAD have not yet been...
9.
Pedraza C, Baltrons M, Heneka M, Garcia A
J Neuroimmunol
. 2003 Nov;
144(1-2):80-90.
PMID: 14597101
We previously showed that soluble guanylyl cyclase (sGC) is down-regulated in astroglial cells after exposure to LPS. Here, we show that this effect is not mediated by released IL-1beta but...
10.
Baltrons M, Pedraza C, Heneka M, Garcia A
Neurobiol Dis
. 2002 Jul;
10(2):139-49.
PMID: 12127152
In astroglial cells beta-amyloid peptides (betaA) induce a reactive phenotype and increase expression of NO synthase. Here we show that treatment of rat brain astrocytes with betaA decreases their capacity...