Carlos E Milla
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Explore the profile of Carlos E Milla including associated specialties, affiliations and a list of published articles.
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62
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1494
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Recent Articles
1.
Dagher I, Kimple A, Ferkol T, Sagel S, Dell S, Milla C, et al.
OTO Open
. 2025 Feb;
9(1):e70079.
PMID: 39989621
Objective: Primary ciliary dyskinesia (PCD) is characterized by upper and lower airway disease. Multiple studies have demonstrated the progression of pulmonary disease; however, longitudinal changes in the otologic and nasal...
2.
Kim M, Chen Q, Echterhof A, Pennetzdorfer N, McBride R, Banaei N, et al.
Nat Commun
. 2024 Nov;
15(1):9987.
PMID: 39609398
Bacteriophage (phage) therapy is a promising therapeutic modality for multidrug-resistant bacterial infections, but its application is mainly limited to personalized therapy due to the narrow host range of individual phages....
3.
Gardner R, Ferkol T, Davis S, Rosenfeld M, Sagel S, Dell S, et al.
Pediatr Pulmonol
. 2024 Nov;
60(1):e27412.
PMID: 39575633
Introduction: Primary ciliary dyskinesia (PCD) management has not been systematically evaluated and is largely empirical. Methods: Pediatric participants with PCD were enrolled in a prospective, longitudinal, multicenter, observational study. Therapies...
4.
Burgener E, Gupta A, Nakano K, Gibbs S, Sommers M, Khosravi A, et al.
J Cyst Fibros
. 2024 Nov;
PMID: 39490215
Background: The Pseudomonas filamentous bacteriophage (Pf) infects Pseudomonas aeruginosa (Pa) and is abundant in the airways of many people with cystic fibrosis (CF) (pwCF). We previously demonstrated that Pf promotes...
5.
Burgener E, Cai P, Kratochvil M, Rojas-Hernandez L, Joo N, Gupta A, et al.
PNAS Nexus
. 2024 Sep;
3(9):pgae390.
PMID: 39301510
is a major pulmonary pathogen causing chronic pulmonary infections in people with cystic fibrosis (CF). The and lysogenic bacteriophage, Pf phage, is abundant in the airways of many people with...
6.
Popescu M, Haddock N, Burgener E, Rojas-Hernandez L, Kaber G, Hargil A, et al.
Viruses
. 2024 Jan;
16(1).
PMID: 38275975
Background: The inovirus Pf4 is a lysogenic bacteriophage of (). People with Cystic Fibrosis (pwCF) experience chronic airway infection with and a significant proportion have high numbers of Pf4 in...
7.
Vladar E, Kunimoto K, Rojas-Hernandez L, Spano J, Sellers Z, Joo N, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Apr;
324(6):L771-L782.
PMID: 37039381
Multiciliated cell loss is a hallmark of airway epithelial remodeling in chronic inflammatory airway diseases including cystic fibrosis (CF), asthma, and chronic obstructive pulmonary disease. It disrupts mucociliary clearance, which...
8.
Laterality Defects in Primary Ciliary Dyskinesia: Relationship to Ultrastructural Defect or Genotype
Barber A, Shapiro A, Davis S, Ferkol T, Atkinson J, Sagel S, et al.
Ann Am Thorac Soc
. 2022 Nov;
20(3):397-405.
PMID: 36342963
The association between organ laterality abnormalities and ciliary ultrastructural defect or genotype in primary ciliary dyskinesia is poorly understood. To determine if there is an association between presence and/or type...
9.
Kratochvil M, Kaber G, Demirdjian S, Cai P, Burgener E, Nagy N, et al.
JCI Insight
. 2022 Jun;
7(12).
PMID: 35730564
Thick, viscous respiratory secretions are a major pathogenic feature of COVID-19, but the composition and physical properties of these secretions are poorly understood. We characterized the composition and rheological properties...
10.
Rosser J, Nagy N, Goel R, Kaber G, Demirdjian S, Saxena J, et al.
J Clin Invest
. 2022 May;
132(9).
PMID: 35499083
BACKGROUNDHyaluronan (HA), an extracellular matrix glycosaminoglycan, has been implicated in the pathophysiology of COVID-19 infection, pulmonary hypertension, pulmonary fibrosis, and other diseases, but is not targeted by any approved drugs....