Carlos A Valverde
Overview
Explore the profile of Carlos A Valverde including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
584
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0
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Recent Articles
1.
Mattiazzi A, Jaquenod De Giusti C, Valverde C
J Physiol
. 2025 Feb;
PMID: 39907446
The multifunctional Ca/calmodulin-dependent protein kinase II (CaMKII) regulates numerous proteins involved in excitation-contraction-relaxation coupling and cardiac excitability. However, its overactivation induces severe Ca/handling alterations, playing a significant role in the...
2.
Coto J, Pereyra E, Cavalli F, Valverde C, Caldiz C, Mate S, et al.
Pflugers Arch
. 2024 Apr;
476(7):1109-1123.
PMID: 38625371
The myocardium is a highly oxidative tissue in which mitochondria are essential to supply the energy required to maintain pump function. When pathological hypertrophy develops, energy consumption augments and jeopardizes...
3.
Santalla M, Garcia A, Mattiazzi A, Valverde C, Schiemann R, Paululat A, et al.
PLoS One
. 2022 May;
17(5):e0267156.
PMID: 35588119
Appropriate cardiac performance depends on a tightly controlled handling of Ca2+ in a broad range of species, from invertebrates to mammals. The role of the Ca2+ ATPase, SERCA, in Ca2+...
4.
Di Mattia R, Diaz Zegarra L, Valverde C, Blanco P, Jaquenod De Giusti C, Portiansky E, et al.
Front Cardiovasc Med
. 2022 May;
9:862118.
PMID: 35548416
Cardiac cells depend on specific sarcolemmal ion transporters to assure the correct intracellular pH regulation. The sodium/bicarbonate cotransporter (NBC) is one of the major alkalinizing mechanisms. In the heart two...
5.
Sommese L, Racioppi M, Shen X, Orlowski A, Valverde C, Louch W, et al.
Pflugers Arch
. 2022 Mar;
474(6):625-636.
PMID: 35235009
Systolic Ca transients are shaped by the concerted summation of Ca sparks across cardiomyocytes. At high pacing rates, alterations of excitation-contraction coupling manifest as pro-arrhythmic Ca alternans that can be...
6.
Santalla M, Gomez I, Valverde C, Ferrero P
Bio Protoc
. 2022 Jan;
11(23):e4244.
PMID: 35005089
has been used to test drugs of abuse, substances with potential benefits for medical purposes, as well as contaminants and hazardous volatile compounds. This model has also been used for...
7.
Valverde C, Mattiazzi A
J Physiol
. 2022 Jan;
600(6):1533-1534.
PMID: 35001395
No abstract available.
8.
Santalla M, Pagola L, Gomez I, Balcazar D, Valverde C, Ferrero P
Biol Open
. 2021 Jan;
10(2).
PMID: 33431431
Studies about the relationship between substances consumed by humans and their impact on health, in animal models, have been a challenge due to differences between species in the animal kingdom....
9.
Cely-Ortiz A, Felice J, Diaz-Zegarra L, Valverde C, Federico M, Palomeque J, et al.
J Gen Physiol
. 2020 Sep;
152(11).
PMID: 32986800
Each heartbeat is followed by a refractory period. Recovery from refractoriness is known as Ca2+ release restitution (CRR), and its alterations are potential triggers of Ca2+ arrhythmias. Although the control...
10.
Federico M, Valverde C, Mattiazzi A, Palomeque J
Front Physiol
. 2020 Feb;
10:1630.
PMID: 32038301
The present review focusses on the regulation and interplay of cardiac SR Ca handling proteins involved in SR Ca uptake and release, i.e., SERCa2/PLN and RyR2. Both RyR2 and SERCA2a/PLN...