Carla Freire Celedonio Fernandes
Overview
Explore the profile of Carla Freire Celedonio Fernandes including associated specialties, affiliations and a list of published articles.
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15
Citations
96
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Recent Articles
1.
Diagnostic platforms for snakebite: current approaches and challenges in medically important species
Brilhante-da-Silva N, Roberto S, Reis Prado N, Machado Marinho A, Celedonio Fernandes C, Pereira S
Anal Biochem
. 2025 Feb;
:115823.
PMID: 40021036
Diagnosing snakebite envenoming is a critical aspect of managing this life-threatening condition. Achieving the impacts and clinical applications of the diagnosis of snakebites is important to help clarify the challenges...
2.
Campos Farias B, Kayano A, Barros Luiz M, de Lima A, Suelen da Silva Morais M, Moreira Mendes L, et al.
Toxicon
. 2024 Jun;
247:107837.
PMID: 38945216
Camelid immunoglobulins represent a unique facet of antibody biology, challenging conventional understandings of antibody diversification. IgG2 and IgG3 in particular are composed solely of heavy chains and exhibit a reduced...
3.
Reis Prado N, Brilhante-da-Silva N, Paloschi M, Roberto S, Barreto B, Fraga Vasconcelos J, et al.
Int Immunopharmacol
. 2024 May;
134:112215.
PMID: 38744173
Camelid single-domain antibodies (VHH) represent a promising class of immunobiologicals for therapeutic applications due to their remarkable stability, specificity, and therapeutic potential. To enhance the effectiveness of antivenoms for snakebites,...
4.
Reis Prado N, Brilhante-da-Silva N, Sousa R, Suelen da Silva Morais M, Roberto S, Barros Luiz M, et al.
J Virol Methods
. 2023 Jul;
320:114787.
PMID: 37516366
Viral infections have been the cause of high mortality rates throughout different periods in history. Over the last two decades, outbreaks caused by zoonotic diseases and transmitted by arboviruses have...
5.
da Fonseca A, Caluaco B, Madureira J, Cabongo S, Gaieta E, Djata F, et al.
Mol Biotechnol
. 2023 Jul;
66(8):1919-1933.
PMID: 37490200
Severe Acute Respiratory Syndrome caused by a coronavirus is a recent viral infection. There is no scientific evidence or clinical trials to indicate that possible therapies have demonstrated results in...
6.
da Fonseca A, Cabongo S, Caluaco B, Colares R, Celedonio Fernandes C, Santos H, et al.
J Biomol Struct Dyn
. 2022 Nov;
41(19):9890-9906.
PMID: 36420665
The pandemic caused by Sars-CoV-2 is a viral infection that has generated one of the most significant health problems worldwide. Previous studies report the main protease (Mpro) as a potential...
7.
Borges Leal A, Bezerra C, Silva A, Everson da Silva L, Bezerra L, Almeida-Neto F, et al.
J Biomol Struct Dyn
. 2022 Aug;
41(13):6326-6344.
PMID: 35943030
Coronavirus disease (COVID-19) has the virus that causes the SARS-CoV-2 severe acute respiratory syndrome, which has reached a pandemic proportion, with thousands of deaths worldwide already registered. It has no...
8.
Malaquias A, Marques L, S Pereira S, de Freitas Fernandes C, Maranhao A, Stabeli R, et al.
Int J Biol Macromol
. 2021 Oct;
193(Pt B):1130-1137.
PMID: 34699899
Monoclonal antibodies have contributed to improving the treatment of several diseases. However, limitations related to pharmacokinetic parameters and production costs have instigated the search for alternative products. Camelids produce functional...
9.
Brilhante-da-Silva N, de Oliveira Sousa R, Arruda A, Lima Dos Santos E, Machado Marinho A, Stabeli R, et al.
Mol Diagn Ther
. 2021 Jun;
25(4):439-456.
PMID: 34146333
The distinct biophysical and pharmaceutical properties of camelid single-domain antibodies, referred to as VHHs or nanobodies, are associated with their nanometric dimensions, elevated stability, and antigen recognition capacity. These biomolecules...
10.
Almeida-Neto F, Geysillene Castro Matos M, Machado Marinho E, Marinho M, de Menezes R, Sampaio T, et al.
Biochem Biophys Res Commun
. 2021 Jan;
537:71-77.
PMID: 33387885
The sanitary emergency generated by the pandemic COVID-19, instigates the search for scientific strategies to mitigate the damage caused by the disease to different sectors of society. The disease caused...