Carl McIntosh
Overview
Explore the profile of Carl McIntosh including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
287
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0
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Recent Articles
1.
Yakhnin A, FitzGerald P, McIntosh C, Yakhnin H, KIreeva M, Turek-Herman J, et al.
Proc Natl Acad Sci U S A
. 2020 Aug;
117(35):21628-21636.
PMID: 32817529
Transcription is punctuated by RNA polymerase (RNAP) pausing. These pauses provide time for diverse regulatory events that can modulate gene expression. Transcription elongation factors dramatically affect RNAP pausing in vitro,...
2.
Imashimizu M, Takahashi H, Oshima T, McIntosh C, Bubunenko M, Court D, et al.
Genome Biol
. 2015 Dec;
16:270.
PMID: 26631078
No abstract available.
3.
Imashimizu M, Takahashi H, Oshima T, McIntosh C, Bubunenko M, Court D, et al.
Genome Biol
. 2015 May;
16:98.
PMID: 25976475
Background: Transcription elongation is frequently interrupted by pausing signals in DNA, with downstream effects on gene expression. Transcription errors also induce prolonged pausing, which can lead to a destabilized genome...
4.
Yu W, McIntosh C, Lister R, Zhu I, Han Y, Ren J, et al.
Genome Res
. 2014 Aug;
24(10):1613-23.
PMID: 25170028
Cytosine methylation is critical in mammalian development and plays a role in diverse biologic processes such as genomic imprinting, X chromosome inactivation, and silencing of repeat elements. Several factors regulate...
5.
Yu W, Briones V, Lister R, McIntosh C, Han Y, Lee E, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(16):5890-5.
PMID: 24711395
DNA methylation patterns are established in early embryogenesis and are critical for cellular differentiation. To investigate the role of CG methylation in potential enhancer formation, we assessed H3K4me1 modification in...
6.
Troyer J, Nelson G, Lautenberger J, Chinn L, McIntosh C, Johnson R, et al.
J Infect Dis
. 2011 Apr;
203(10):1491-502.
PMID: 21502085
Background: Host genetic variation influences human immunodeficiency virus (HIV) infection and progression to AIDS. Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study...
7.
Chinn L, Tang M, Kessing B, Lautenberger J, Troyer J, Malasky M, et al.
J Infect Dis
. 2010 Nov;
202(12):1836-45.
PMID: 21083371
Background: High-throughput genome-wide techniques have facilitated the identification of previously unknown host proteins involved in cellular human immunodeficiency virus (HIV) infection. Recently, 3 independent studies have used small interfering RNA...
8.
Sezgin E, Drosdak A, McIntosh C, Kessing B, Lautenberger J, Goedert J, et al.
J Hum Genet
. 2010 Jun;
55(9):613-20.
PMID: 20574427
We attempted to refine the understanding of an association of Y-chromosomal haplogroup I (hg-I) with enhanced AIDS progression that had been previously reported. First, we compared the progression phenotype between...
9.
Troyer J, VandeWoude S, Pecon-Slattery J, McIntosh C, Franklin S, Antunes A, et al.
Vet Immunol Immunopathol
. 2008 Feb;
123(1-2):159-66.
PMID: 18299153
Feline and primate immunodeficiency viruses (FIVs, SIVs, and HIV) are transmitted via direct contact (e.g. fighting, sexual contact, and mother-offspring transmission). This dynamic likely poses a behavioral barrier to cross-species...