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Carl J Franconi

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Recent Articles
1.
Iu D, Maya J, Vu L, Fogarty E, McNairn A, Ahmed F, et al.
Proc Natl Acad Sci U S A . 2024 Dec; 121(50):e2415119121. PMID: 39621903
Myalgic encephalomyelitis/chronic fatigue syndrome (ME) is a severe, debilitating disease, with substantial evidence pointing to immune dysregulation as a key contributor to pathophysiology. To characterize the gene regulatory state underlying...
2.
Keller B, Receno C, Franconi C, Harenberg S, Stevens J, Mao X, et al.
J Transl Med . 2024 Jul; 22(1):627. PMID: 38965566
Background: Post-exertional malaise (PEM), the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), represents a constellation of abnormal responses to physical, cognitive, and/or emotional exertion including profound fatigue, cognitive dysfunction,...
3.
Vu L, Ahmed F, Zhu H, Iu D, Fogarty E, Kwak Y, et al.
Cell Rep Med . 2024 Jan; 5(1):101373. PMID: 38232699
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious and poorly understood disease. To understand immune dysregulation in ME/CFS, we use single-cell RNA sequencing (scRNA-seq) to examine immune cells in patient...
4.
Giloteaux L, Glass K, Germain A, Franconi C, Zhang S, Hanson M
J Extracell Vesicles . 2024 Jan; 13(1):e12403. PMID: 38173127
In healthy individuals, physical exercise improves cardiovascular health and muscle strength, alleviates fatigue and reduces the risk of chronic diseases. Although exercise is suggested as a lifestyle intervention to manage...
5.
Moore G, Keller B, Stevens J, Mao X, Stevens S, Chia J, et al.
Medicina (Kaunas) . 2023 Mar; 59(3). PMID: 36984572
: Post-exertional malaise (PEM) is the hallmark of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), but there has been little effort to quantitate the duration of PEM symptoms following a known exertional...
6.
Germain A, Giloteaux L, Moore G, Levine S, Chia J, Keller B, et al.
JCI Insight . 2022 Mar; 7(9). PMID: 35358096
Post-exertional malaise (PEM) is a hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We monitored the evolution of 1157 plasma metabolites in 60 ME/CFS (45 female, 15 male) and 45...