Carl Hobbs
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Explore the profile of Carl Hobbs including associated specialties, affiliations and a list of published articles.
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64
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1902
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Recent Articles
21.
La Russa F, Lopes D, Hobbs C, Argunhan F, Brain S, Bevan S, et al.
J Invest Dermatol
. 2019 Apr;
139(9):1936-1945.e3.
PMID: 30974165
Increasing evidence suggests that nerve fibers responding to noxious stimuli (nociceptors) modulate immunity in a variety of tissues, including the skin. Yet, the role of nociceptors in regulating sterile cutaneous...
22.
Kolundzic N, Khurana P, Hobbs C, Rogar M, Ropret S, Torma H, et al.
Stem Cell Res
. 2019 Apr;
37:101424.
PMID: 30933721
We have generated MLi002-A, a new induced pluripotent stem cell (iPSC) line derived from keratinocytes of a skin punch biopsy of a female patient with the severe epidermolysis bullosa simplex...
23.
Devito L, Klontzas M, Cvoro A, Galleu A, Simon M, Hobbs C, et al.
Cell Death Dis
. 2019 Mar;
10(4):277.
PMID: 30894508
Variability among donors, non-standardized methods for isolation, and characterization contribute to mesenchymal stem/stromal cell (MSC) heterogeneity. Induced pluripotent stem cell (iPSCs)-derived MSCs would circumvent many of current issues and enable...
24.
Goncalves M, Clarke E, Jarvis C, Kalindjian S, Pitcher T, Grist J, et al.
Bioorg Med Chem Lett
. 2019 Feb;
29(8):995-1000.
PMID: 30792038
Oxadiazole replacement of an amide linkage in an RARα agonist template 1, followed by lead optimisation, has produced a highly potent and selective RARβ agonist 4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-oxadiazol-3-yl)benzoic acid (10) with good...
25.
Cleary S, Hobbs C, Amison R, Arnold S, OShaughnessy B, Lefrancais E, et al.
Am J Respir Cell Mol Biol
. 2019 Feb;
61(2):232-243.
PMID: 30768917
Platelets are recruited to inflammatory foci and contribute to host defense and inflammatory responses. Compared with platelet recruitment in hemostasis and thrombosis, the mechanisms of platelet recruitment in inflammation and...
26.
Goncalves M, Wu Y, Clarke E, Grist J, Hobbs C, Trigo D, et al.
J Neurosci
. 2019 Feb;
39(16):3013-3027.
PMID: 30760627
In the CNS, oligodendrocytes are responsible for myelin formation and maintenance. Following spinal cord injury, oligodendrocyte loss and an inhibitory milieu compromise remyelination and recovery. Here, we explored the role...
27.
Strotton M, Bodey A, Wanelik K, Darrow M, Medina E, Hobbs C, et al.
Sci Rep
. 2018 Aug;
8(1):12017.
PMID: 30104610
Synchrotron radiation microtomography (SRμCT) is a nominally non-destructive 3D imaging technique which can visualise the internal structures of whole soft tissues. As a multi-stage technique, the cumulative benefits of optimising...
28.
Devito L, Donne M, Kolundzic N, Khurana P, Hobbs C, Kaddour G, et al.
Stem Cell Res
. 2018 Aug;
31:122-126.
PMID: 30075366
We have generated an induced pluripotent stem cell (iPSC) line KCLi001-A (iOP118) from a female atopic dermatitis (AD) patient, heterozygous for the loss-of-function mutation c.2282del4 in the filaggrin gene (FLG)....
29.
Baldascino E, Di Cristina G, Tedesco P, Hobbs C, Shaw T, Ponte G, et al.
Front Physiol
. 2018 Jan;
8:1001.
PMID: 29326594
The gastric ganglion is the largest visceral ganglion in cephalopods. It is connected to the brain and is implicated in regulation of digestive tract functions. Here we have investigated the...
30.
Goncalves M, Wu Y, Trigo D, Clarke E, Malmqvist T, Grist J, et al.
Neurobiol Dis
. 2017 Dec;
111:70-79.
PMID: 29274429
Stimulation of retinoic acid (RA) mediated signalling pathways following neural injury leads to regeneration in the adult nervous system and numerous studies have shown that the specific activation of the...