Carl D Bortner
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Explore the profile of Carl D Bortner including associated specialties, affiliations and a list of published articles.
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53
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1425
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Recent Articles
11.
Childers G, Perry C, Blachut B, Martin N, Bortner C, Sieber S, et al.
Environ Health Perspect
. 2021 Apr;
129(4):47015.
PMID: 33929904
Background: Mitochondrial function is implicated as a target of environmental toxicants and found in disease or injury models, contributing to acute and chronic inflammation. One mechanism by which mitochondrial damage...
12.
Bortner C, Cidlowski J
Front Cell Dev Biol
. 2020 Dec;
8:611211.
PMID: 33324655
The movement of water across the cell membrane is a natural biological process that occurs during growth, cell division, and cell death. Many cells are known to regulate changes in...
13.
Cain D, Bortner C, Diaz-Jimenez D, Petrillo M, Gruver-Yates A, Cidlowski J
J Immunol
. 2020 Jun;
205(3):619-629.
PMID: 32571841
Glucocorticoids promote CXCR4 expression by T cells, monocytes, macrophages, and eosinophils, but it is not known if glucocorticoids regulate CXCR4 in B cells. Considering the important contributions of CXCR4 to...
14.
Liu J, Yu L, Castro L, Yan Y, Sifre M, Bortner C, et al.
Arch Toxicol
. 2019 Aug;
93(10):2773-2785.
PMID: 31468104
Cadmium (Cd) is a ubiquitous environmental metal that is reported to be a "metalloestrogen." Uterine leiomyomas (fibroids) are estrogen-responsive gynecologic neoplasms that can be the target of xenoestrogens. Previous epidemiology...
15.
Yu L, Das P, Vall A, Yan Y, Gao X, Sifre M, et al.
Mol Cell Endocrinol
. 2019 Jan;
484:59-68.
PMID: 30615907
The role of ERα36 in regulating BPA's effects and its potential as a risk factor for human uterine fibroids were evaluated. BPA at low concentrations (10 μM - 10 μM)...
16.
Sinha B, Bortner C, Mason R, Cannon R
Biochim Biophys Acta Gen Subj
. 2018 Sep;
1862(12):2806-2814.
PMID: 30251669
Background: Development of resistance to chemotherapy drugs is a significant problem in treating human malignancies in the clinic. Overexpression of drug efflux proteins, including P-170 glycoprotein (P-gp), an ATP-dependent efflux...
17.
Sinha B, van T Erve T, Kumar A, Bortner C, Motten A, Mason R
Free Radic Biol Med
. 2017 Oct;
113:406-412.
PMID: 29079526
Topotecan, a derivative of camptothecin, is an important anticancer drug for the treatment of various human cancers in the clinic. While the principal mechanism of tumor cell killing by topotecan...
18.
Kang H, Chen L, Lichti-Kaiser K, Liao G, Gerrish K, Bortner C, et al.
Stem Cells
. 2016 Jun;
34(11):2772-2783.
PMID: 27350140
In this study, we identify a novel and essential role for the Krüppel-like zinc finger transcription factor GLI-similar 3 (GLIS3) in the regulation of postnatal spermatogenesis. We show that GLIS3...
19.
Sharma N, Kumar A, Kumari A, Tokar E, Waalkes M, Bortner C, et al.
PLoS One
. 2015 Nov;
10(11):e0141897.
PMID: 26540186
Camptothecin (CPT), a topoisomerase I poison, is an important drug for the treatment of solid tumors in the clinic. Nitric oxide (·NO), a physiological signaling molecule, is involved in many...
20.
Joo J, Ueda E, Bortner C, Yang X, Liao G, Jetten A
Biochem Pharmacol
. 2015 Aug;
97(3):256-68.
PMID: 26275811
In this study, we demonstrate that treatment of T lymphoblastic leukemic Molt4 cells with farnesol activates the apoptosome via the intrinsic pathway of apoptosis. This induction was associated with changes...