Carina Seidl
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Explore the profile of Carina Seidl including associated specialties, affiliations and a list of published articles.
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7
Citations
78
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Recent Articles
1.
Niehrs C, Seidl C, Lee H
Bioessays
. 2024 Aug;
46(10):e2400144.
PMID: 39180250
R-spondins (RSPOs) are a family of secreted proteins and stem cell growth factors that are potent co-activators of Wnt signaling. Recently, RSPO2 and RSPO3 were shown to be multifunctional, not...
2.
Niehrs C, Da Silva F, Seidl C
Trends Cell Biol
. 2024 May;
35(1):24-32.
PMID: 38697898
Cilia and Wnt signaling have a complex relationship, wherein Wnt regulates cilia and, conversely, cilia may affect Wnt signaling. Recently, it was shown that Wnt receptors are present in flagella,...
3.
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C
Nat Commun
. 2023 Mar;
14(1):1259.
PMID: 36878953
It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile cilia are signaling-inert nanomotors. Contrasting both views, we here show in the mucociliary epidermis of X....
4.
Zhang K, Da Silva F, Seidl C, Wilsch-Brauninger M, Herbst J, Huttner W, et al.
Dev Cell
. 2023 Jan;
58(2):139-154.e8.
PMID: 36693320
WNT signaling is important in development, stem cell maintenance, and disease. WNT ligands typically signal via receptor activation across the plasma membrane to induce β-catenin-dependent gene activation. Here, we show...
5.
Groestlinger J, Seidl C, Varga E, Del Favero G, Marko D
Front Nutr
. 2022 Jul;
9:882222.
PMID: 35811943
The human gastrointestinal tract is an important site of nutrient absorption and a crucial barrier against xenobiotics. It regularly faces "chemical cocktails" composed of food constituents, their human and microbial...
6.
Lee H, Seidl C, Sun R, Glinka A, Niehrs C
Nat Commun
. 2020 Nov;
11(1):5570.
PMID: 33149137
BMP signaling plays key roles in development, stem cells, adult tissue homeostasis, and disease. How BMP receptors are extracellularly modulated and in which physiological context, is therefore of prime importance....
7.
Seidl C, Panzitt K, Bertsch A, Brcic L, Schein S, Mack M, et al.
Cancer Lett
. 2019 Nov;
469:266-276.
PMID: 31697978
Lung cancer is one of the deadliest cancers worldwide. Late diagnosis at an advanced, inoperable stage makes chemotherapy a treatment of choice, yet, with low response rates. The hedgehog signaling...