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Cameron P Beaudreault

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Recent Articles
1.
Beaudreault C, Wang R, Muh C, Rosenberg A, Funari A, McGoldrick P, et al.
Brain Sci . 2024 Oct; 14(10). PMID: 39452039
Background: Cell-based therapies for drug-resistant epilepsy using induced pluripotent stem cell-derived inhibitory interneurons are now in early-phase clinical trials, building on findings from trials in Parkinson's disease (PD) and Huntington's...
2.
Brabant P, Beaudreault C, Wolf S, McGoldrick P, Ghatan S, Muh C
J Neurosurg Case Lessons . 2024 Oct; 8(15). PMID: 39378523
Background: Responsive neurostimulation (RNS) is often considered to be a palliative therapy for drug-resistant epilepsy (DRE) and is generally not considered to be a treatment for patients with tuberous sclerosis...
3.
Beaudreault C, Spirollari E, Zeller S, Oguguo O, Wainwright J, Mohan A, et al.
Neurosurgery . 2024 Sep; 96(4):794-801. PMID: 39248516
Background And Objectives: Although ventriculoperitoneal (VP) shunts are a common treatment for hydrocephalus, there are complication risks including infections. Late complications such as ventriculitis from ascending abdominal infections can have...
4.
Beaudreault C, Chiang S, Sacknovitz A, Moss R, Brabant P, Zuckerman D, et al.
Epilepsy Behav . 2024 Sep; 159:110008. PMID: 39222605
Objective: To assess the impact of vagus nerve stimulation (VNS) on quality of life contributors such as rescue medications. Methods: Using the seizure diary application SeizureTracker™ database, we examined trends...
5.
Muh C, Dorilio J, Beaudreault C, McGoldrick P, Pisapia J, Wolf S
Childs Nerv Syst . 2024 Mar; 40(5):1331-1337. PMID: 38451299
Purpose: Stereoelectroencephalography (SEEG) is a diagnostic surgery that implants electrodes to identify areas of epileptic onset in patients with drug-resistant epilepsy (DRE). SEEG is effective in identifying the epileptic zone;...
6.
Zuckerman D, Beaudreault C, Muh C, McGoldrick P, Wolf S
J Neurosurg Case Lessons . 2023 Nov; 6(22). PMID: 38011695
Background: Myasthenia gravis (MG) is an autoimmune disorder in which the postsynaptic acetylcholine receptor of the neuromuscular junction is destroyed by autoantibodies. The authors report a case of MG in...
7.
Beaudreault C, Spirollari E, Naftchi A, Sukul V, Das A, Vazquez S, et al.
J Neurosurg Pediatr . 2023 Mar; 31(6):565-573. PMID: 36933267
Objective: The aim of this study was to assess the safety and efficacy of combined active responsive neurostimulation (RNS) and vagus nerve stimulation (VNS) therapies in pediatric patients with drug-resistant...
8.
Zhu Q, Mishra A, Park J, Liu D, Le D, Gonzalez S, et al.
Neuron . 2023 Jan; 111(6):807-823.e7. PMID: 36626901
Previously, we demonstrated the efficacy of human pluripotent stem cell (hPSC)-derived GABAergic cortical interneuron (cIN) grafts in ameliorating seizures. However, a safe and reliable clinical translation requires a mechanistic understanding...
9.
Beaudreault C, Muh C, Naftchi A, Spirollari E, Das A, Vazquez S, et al.
Front Hum Neurosci . 2022 May; 16:876204. PMID: 35496067
Background: Responsive neurostimulation (RNS System) has been utilized as a treatment for intractable epilepsy. The RNS System delivers stimulation in response to detected abnormal activity, via leads covering the seizure...
10.
Park G, Noh H, Shao Z, Ni P, Qin Y, Liu D, et al.
Nat Neurosci . 2020 Oct; 23(11):1352-1364. PMID: 33097921
The mechanisms by which prenatal immune activation increase the risk for neuropsychiatric disorders are unclear. Here, we generated developmental cortical interneurons (cINs)-which are known to be affected in schizophrenia (SCZ)...