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Callaghan R Garland

Explore the profile of Callaghan R Garland including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Dutton A, Turnbaugh E, Patel C, Garland C, Taylor S, Alers-Velazquez R, et al.
PLoS Pathog . 2025 Feb; 21(2):e1012935. PMID: 39919123
Neonatal herpes simplex virus (nHSV) is a devastating infection impacting approximately 14,000 newborns globally each year. nHSV infection is associated with high neurologic morbidity and mortality, making early intervention critical....
2.
Slein M, Backes I, Kelkar N, Garland C, Khanwalkar U, Sholukh A, et al.
bioRxiv . 2024 Nov; PMID: 39605495
Herpes simplex virus (HSV) encodes surface glycoproteins that are host defense evasion molecules, allowing the virus to escape immune clearance. In addition to their role in neuropathogenesis and cell-cell spread,...
3.
Slein M, Backes I, Garland C, Kelkar N, Leib D, Ackerman M
Cell Rep Med . 2024 Feb; 5(2):101417. PMID: 38350452
Multiple failed herpes simplex virus (HSV) vaccine candidates induce robust neutralizing antibody (Ab) responses in clinical trials, raising the hypothesis that Fc-domain-dependent effector functions may be critical for protection. While...
4.
Slein M, Backes I, Garland C, Kelkar N, Leib D, Ackerman M
bioRxiv . 2023 Sep; PMID: 37693377
The failure of multiple herpes simplex virus (HSV) vaccine candidates that induce neutralizing antibody responses raises the hypothesis that other activities, such as Fc domain-dependent effector functions, may be critical...
5.
Backes I, Byrd B, Slein M, Patel C, Taylor S, Garland C, et al.
J Exp Med . 2022 Sep; 219(12). PMID: 36156707
Neonatal herpes simplex virus (nHSV) infections often result in significant mortality and neurological morbidity despite antiviral drug therapy. Maternally transferred herpes simplex virus (HSV)-specific antibodies reduce the risk of clinically...