Caitlin E Tolbert
Overview
Explore the profile of Caitlin E Tolbert including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
190
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Recent Articles
1.
Tolbert C, Palmquist L, Dixon H, Srougi M
J Vis Exp
. 2019 Oct;
(152).
PMID: 31657795
The adhesion and spreading of cells onto the extracellular matrix (ECM) are essential cellular processes during organismal development and for the homeostasis of adult tissues. Interestingly, oxidative stress can alter...
2.
Tolbert C, Beck M, Kilmer C, Srougi M
Biochem Biophys Res Commun
. 2018 Dec;
508(4):1155-1161.
PMID: 30553448
Ataxia-telangiectasia mutated (ATM) is a serine-threonine kinase that is integral in the response to DNA double-stranded breaks (DSBs). Cells and tissues lacking ATM are prone to tumor development and enhanced...
3.
Thompson P, Ramachandran S, Case L, Tolbert C, Tandon A, Pershad M, et al.
Structure
. 2017 Jan;
25(2):264-275.
PMID: 28089450
Vinculin, a scaffolding protein that localizes to focal adhesions (FAs) and adherens junctions, links the actin cytoskeleton to the adhesive super-structure. While vinculin binds to a number of cytoskeletal proteins,...
4.
Scott D, Tolbert C, Burridge K
Mol Biol Cell
. 2016 Mar;
27(9):1420-30.
PMID: 26985018
Junctional adhesion molecule A (JAM-A) is a broadly expressed adhesion molecule that regulates cell-cell contacts and facilitates leukocyte transendothelial migration. The latter occurs through interactions with the integrin LFA-1. Although...
5.
Scott D, Tolbert C, Graham D, Wittchen E, Bear J, Burridge K
Mol Biol Cell
. 2015 Jul;
26(18):3205-14.
PMID: 26224316
Junctional adhesion molecule-A (JAM-A) is an adherens and tight junction protein expressed by endothelial and epithelial cells. JAM-A serves many roles and contributes to barrier function and cell migration and...
6.
Tolbert C, Thompson P, Superfine R, Burridge K, Campbell S
Biochemistry
. 2014 Aug;
53(34):5526-36.
PMID: 25115937
Vinculin is an essential structural adaptor protein that localizes to sites of adhesion and is involved in a number of cell processes including adhesion, spreading, motility, force transduction, and cell...
7.
Thompson P, Tolbert C, Shen K, Kota P, Palmer S, Plevock K, et al.
Structure
. 2014 Apr;
22(5):697-706.
PMID: 24685146
Vinculin, a cytoskeletal scaffold protein essential for embryogenesis and cardiovascular function, localizes to focal adhesions and adherens junctions, connecting cell surface receptors to the actin cytoskeleton. While vinculin interacts with...
8.
Montgomery E, Temple B, Peters K, Tolbert C, Booker B, Martin J, et al.
Mol Pharmacol
. 2014 Jan;
85(4):586-97.
PMID: 24435554
The G12/13 class of heterotrimeric G proteins, comprising the α-subunits Gα12 and Gα13, regulates multiple aspects of cellular behavior, including proliferation and cytoskeletal rearrangements. Although guanine nucleotide exchange factors for...
9.
Thompson P, Tolbert C, Campbell S
FEBS Lett
. 2013 Mar;
587(8):1220-9.
PMID: 23466368
Vinculin, and its splice variant metavinculin, are scaffolding proteins that localize to cellular adhesions. Vinculin is a key player in mediating cell adhesion, motility, and cellular response to force. In...
10.
Tolbert C, Burridge K, Campbell S
Cell Adh Migr
. 2013 Jan;
7(2):219-25.
PMID: 23307141
Vinculin is an essential cell adhesion protein, found at both focal adhesions and adherens junctions, where it couples transmembrane proteins to the actin cytoskeleton. Vinculin is involved in controlling cell...