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Cailin E Joyce

Explore the profile of Cailin E Joyce including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 852
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Recent Articles
1.
Schneider R, Schenone M, Ferreira M, Kramann R, Joyce C, Hartigan C, et al.
Nat Med . 2024 Oct; 30(11):3382. PMID: 39443719
No abstract available.
2.
Chan D, Xu J, Vujovic A, Wong N, Gordon V, de Rooij L, et al.
Blood Adv . 2021 Aug; 5(16):3120-3133. PMID: 34406376
How hematopoietic stem cells (HSCs) coordinate their divisional axis and whether this orientation is important for stem cell-driven hematopoiesis is poorly understood. Single-cell RNA sequencing data from patients with Shwachman-Diamond...
3.
Grossman J, Vasudevan D, Joyce C, Hildago M
Oncogene . 2021 Jan; 40(8):1393-1395. PMID: 33500548
No abstract available.
4.
Chou D, Frismantas V, Milton Y, David R, Pop-Damkov P, Ferguson D, et al.
Nat Biomed Eng . 2020 Feb; 4(4):477. PMID: 32051581
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
5.
Chou D, Frismantas V, Milton Y, David R, Pop-Damkov P, Ferguson D, et al.
Nat Biomed Eng . 2020 Jan; 4(4):394-406. PMID: 31988457
The inaccessibility of living bone marrow (BM) hampers the study of its pathophysiology under myelotoxic stress induced by drugs, radiation or genetic mutations. Here, we show that a vascularized human...
6.
House N, Polleys E, Quasem I, De la Rosa Mejia M, Joyce C, Takacsi-Nagy O, et al.
Elife . 2019 Dec; 8. PMID: 31804179
CAG/CTG trinuncleotide repeats are fragile sequences that when expanded form DNA secondary structures and cause human disease. We evaluated CAG/CTG repeat stability and repair outcomes in histone H2 mutants in...
7.
Joyce C, Saadatpour A, Ruiz-Gutierrez M, Bolukbasi O, Jiang L, Thomas D, et al.
J Clin Invest . 2019 Jun; 129(9):3821-3826. PMID: 31211692
Shwachman-Diamond Syndrome (SDS) is a rare and clinically-heterogeneous bone marrow (BM) failure syndrome caused by mutations in the Shwachman-Bodian-Diamond Syndrome (SBDS) gene. Although SDS was described over 50 years ago,...
8.
Ruiz-Gutierrez M, Bolukbasi O, Alexe G, Kotini A, Ballotti K, Joyce C, et al.
JCI Insight . 2019 May; 5. PMID: 31039138
Monosomy 7 or deletion of 7q (del(7q)) are common clonal cytogenetic abnormalities associated with high grade myelodysplastic syndrome (MDS) arising in inherited and acquired bone marrow failure. Current non-transplant approaches...
9.
Koch M, House N, Cosetta C, Jong R, Salomon C, Joyce C, et al.
Genetics . 2018 Jan; 208(3):963-976. PMID: 29305386
CAG/CTG trinucleotide repeats are unstable sequences that are difficult to replicate, repair, and transcribe due to their structure-forming nature. CAG repeats strongly position nucleosomes; however, little is known about the...
10.
Hao-Ru Hsu J, Hubbell-Engler B, Adelmant G, Huang J, Joyce C, Vazquez F, et al.
Cancer Res . 2017 Jun; 77(17):4613-4625. PMID: 28655788
Through an shRNA screen, we identified the protein arginine methyltransferase Prmt1 as a vulnerable intervention point in murine p53/Rb-null osteosarcomas, the human counterpart of which lacks effective therapeutic options. Depletion...