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C Valetti

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Articles 9
Citations 424
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Recent Articles
1.
dAddio M, Pizzigoni A, Bassi M, Baschirotto C, Valetti C, Incerti B, et al.
Hum Mol Genet . 2000 Dec; 9(20):3011-8. PMID: 11115845
Ocular albinism type 1 (OA1) is an X-linked disorder mainly characterized by a severe reduction of visual acuity, hypopigmentation of the retina and the presence of macromelanosomes in the skin...
2.
Valetti C, Wetzel D, Schrader M, Hasbani M, Gill S, Kreis T, et al.
Mol Biol Cell . 1999 Dec; 10(12):4107-20. PMID: 10588646
The flow of material from peripheral, early endosomes to late endosomes requires microtubules and is thought to be facilitated by the minus end-directed motor cytoplasmic dynein and its activator dynactin....
3.
Schiaffino M, dAddio M, Alloni A, Baschirotto C, Valetti C, Cortese K, et al.
Nat Genet . 1999 Sep; 23(1):108-12. PMID: 10471510
G protein-coupled receptors (GPCRs) participate in the most common signal transduction system at the plasma membrane. The wide distribution of heterotrimeric G proteins in the internal membranes suggests that a...
4.
Scheel J, Pierre P, Rickard J, Diamantopoulos G, Valetti C, van der Goot F, et al.
J Biol Chem . 1999 Aug; 274(36):25883-91. PMID: 10464331
We have purified authentic CLIP-170 (cytoplasmic linker protein of 170 kDa) and fragments comprising functional domains of the protein to characterize the structural basis of the function of CLIP-170. Analysis...
5.
Goodson H, Valetti C, Kreis T
Curr Opin Cell Biol . 1997 Feb; 9(1):18-28. PMID: 9013678
The cytoskeleton is essential for the proper function of many components of secretory and endocytic pathways, and the importance both of microtubule motors (kinesins and dyneins) and of actin motors...
6.
Valetti C, Sitia R
Mol Biol Cell . 1994 Dec; 5(12):1311-24. PMID: 7696712
Dithiothreitol (DTT) blocks the endoplasmic reticulum (ER)-Golgi transport of newly synthesized immunoglobulin (Ig) molecules, whereas 2-mercaptoethanol (2ME) allows secretion of unpolymerized Igs otherwise retained intracellularly by disulphide interchange reactions. To...
7.
Valetti C, Grossi C, Milstein C, Sitia R
J Cell Biol . 1991 Nov; 115(4):983-94. PMID: 1955467
Dilated cisternae of the ER resembling Russell Bodies (RBs) are induced in light (L) chain producing myeloma cell lines by transfection of a mu heavy (H) chain gene lacking the...
8.
Fra A, Alberini C, Bet P, Finazzi D, Valetti C, Sitia R
Ann Biol Clin (Paris) . 1991 Jan; 49(5):283-6. PMID: 1928844
Cells have means to ensure that only properly folded and assembled molecules are transported to their final destination, a phenomenon referred to as "quality control" of protein synthesis. Thus, plasma...
9.
Sitia R, Neuberger M, Alberini C, Bet P, Fra A, Valetti C, et al.
Cell . 1990 Mar; 60(5):781-90. PMID: 2107027
B lymphocytes do not secrete IgM, and plasma cells only secrete IgM polymers. Here we show that both events are attributable to the tailpiece found at the carboxyl terminus of...