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C Terwinghe

Explore the profile of C Terwinghe including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 5
Citations 72
Followers 0
Related Specialties
Biochemistry
Radiology
Chemistry
Top 10 Co-Authors
A Verbruggen
L Mortelmans
T Verduyckt
K Serdons
G Bormans
D Vanderghinste
J Cleynhens
M Van Eeckhoudt
A Lopez Medina
N Cherbuin
Published In
Bioorg Med Chem Lett
J Pharm Biomed Anal
EJNMMI Phys
Eur Radiol
Affiliations
Soon will be listed here.
Recent Articles
1.
How much do Ga-, Lu- and I-based radiopharmaceuticals contribute to the global radiation exposure of nuclear medicine staff?
Struelens L, Aalbersberg E, Beels L, Cherbuin N, DAsseler Y, De Monte F, et al.
EJNMMI Phys . 2024 Nov; 11(1):95. PMID: 39540964
Background: The radiation exposure of nuclear medicine personnel, especially concerning extremity doses, has been a significant focus over the past two decades. This study addresses the evolving practice of NM,...
2.
Comparison of diagnostic accuracy of (111)In-pentetreotide SPECT and (68)Ga-DOTATOC PET/CT: A lesion-by-lesion analysis in patients with metastatic neuroendocrine tumours
Van Binnebeek S, Vanbilloen B, Baete K, Terwinghe C, Koole M, Mottaghy F, et al.
Eur Radiol . 2015 Jul; 26(3):900-9. PMID: 26162577
Objectives: To compare the diagnostic accuracy of (111)In-pentetreotide-scintigraphy with (68)Ga-DOTATOC-positron emission tomography (PET)/computed tomography (CT) in patients with metastatic-neuroendocrine tumour (NET) scheduled for peptide receptor radionuclide therapy (PRRT). Incremental lesions...
3.
Synthesis of 18F-labelled 2-(4'-fluorophenyl)-1,3-benzothiazole and evaluation as amyloid imaging agent in comparison with [11C]PIB
Serdons K, Verduyckt T, Vanderghinste D, Cleynhens J, Borghgraef P, Vermaelen P, et al.
Bioorg Med Chem Lett . 2009 Jan; 19(3):602-5. PMID: 19147351
2-(4'-[(18)F]fluorophenyl)-1,3-benzothiazole was synthesized as a fluorine-18 labelled derivative of the Pittsburg Compound-B (PIB), which has known affinity for amyloid beta and promising characteristics as tracer for in vivo visualisation of...
4.
Synthesis and evaluation of a (99m)Tc-BAT-phenylbenzothiazole conjugate as a potential in vivo tracer for visualization of amyloid beta
Serdons K, Verduyckt T, Cleynhens J, Terwinghe C, Mortelmans L, Bormans G, et al.
Bioorg Med Chem Lett . 2007 Oct; 17(22):6086-90. PMID: 17904367
We have conjugated S,S'-bis-trityl-N-BOC-N'-acetic acid-1,2-ethylenedicysteamine, a protected bis-amino-bis-thiol (BAT) tetraligand, with 2-(4'-aminophenyl)-1,3-benzothiazole, a derivative of thioflavin-T with known affinity for amyloid. The conjugate was efficiently labelled with (99m)Tc by heating...
5.
An efficient HPLC method for the analysis of isomeric purity of technetium-99m-exametazime and identity confirmation using LC-MS
Vanderghinste D, Van Eeckhoudt M, Terwinghe C, Mortelmans L, Bormans G, Verbruggen A, et al.
J Pharm Biomed Anal . 2003 Aug; 32(4-5):679-85. PMID: 12899958
99mTc-exametazime (99mTc-d,l-HMPAO, 99mTc-d,l-hexamethylpropyleneamine oxime) is a neutral rather unstable complex of short-lived 99mTc (t(1/2)=6 h) with the d,l-isomer (mixture of D,D- and L,L-isomers) of a bis-amine bis-oxime tetraligand. It is...