C Taggart
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Explore the profile of C Taggart including associated specialties, affiliations and a list of published articles.
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15
Citations
392
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0
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Recent Articles
1.
McNally P, Coughlan C, Bergsson G, Doyle M, Taggart C, Adorini L, et al.
J Cyst Fibros
. 2011 Jul;
10(6):428-34.
PMID: 21784717
Background: 1,25-Dihydroxycholecalciferol (1,25(OH)(2)D(3)) has been shown to mitigate epithelial inflammatory responses after antigen exposure. Patients with cystic fibrosis (CF) are at particular risk for vitamin D deficiency. This may contribute...
2.
Caird J, Napoli C, Taggart C, Farrell M, Bouchier-Hayes D
Eur J Neurol
. 2006 Sep;
13(10):1098-105.
PMID: 16987162
Matrix metalloproteinases 2 and 9 (MMP 2 and -9) have been implicated in the pathogenesis of atherosclerosis and aneurysm formation. The goal of the study was to establish the role...
3.
Coakley R, Taggart C, Greene C, McElvaney N, ONeill S
J Leukoc Biol
. 2002 Apr;
71(4):603-10.
PMID: 11927646
Although neutrophils are a critical component of the inflammatory process, their functional regulation is incompletely understood. Of note, although pCO2 varies physiologically and pathologically in the neutrophilic milieu, its affect...
4.
Rooney C, Taggart C, Coakley R, McElvaney N, ONeill S
Am J Respir Cell Mol Biol
. 2001 Jun;
24(6):747-54.
PMID: 11415941
Wegener's granulomatosis (WG) is classically associated with the presence of cytoplasmic antineutrophil cytoplasmic autoantibodies (c-ANCA). Proteinase 3 (PR3), the target antigen for c-ANCA, is inhibited by the antiprotease alpha1-antitrypsin (A1AT),...
5.
Coakley R, Taggart C, ONeill S, McElvaney N
Am J Med Sci
. 2001 Feb;
321(1):33-41.
PMID: 11202478
Alpha1-antitrypsin (alpha1AT) deficiency is a common lethal hereditary disorder of white persons of European descent. The condition is characterized by reduced serum levels of alpha1AT, a 52-kDa glycoprotein synthesized chiefly...
6.
Coakley R, Taggart C, Canny G, Greally P, ONeill S, McElvaney N
Am J Physiol Lung Cell Mol Physiol
. 2000 Jul;
279(1):L66-74.
PMID: 10893204
Cystic fibrosis (CF) is a condition characterized by neutrophil-mediated lung damage and bacterial colonization. The physiological basis for reported functional alterations in CF neutrophils, including increased release of neutrophil elastase,...
7.
Taggart C, Kim G, McElvaney N, Wehr N, Moss J, Levine R
J Biol Chem
. 2000 Jun;
275(35):27258-65.
PMID: 10867014
Hydrogen peroxide is a component of cigarette smoke known to be essential for inactivation of alpha(1)-antitrypsin, the primary inhibitor of neutrophil elastase. To establish the molecular basis of the inactivation...
8.
Taggart C, Coakley R, Greally P, Canny G, ONeill S, McElvaney N
Am J Physiol Lung Cell Mol Physiol
. 2000 Jan;
278(1):L33-41.
PMID: 10645888
Cystic fibrosis (CF) is a lethal, hereditary disorder characterized by a neutrophil-dominated inflammation of the lung. We sought to determine whether neutrophils from individuals with CF release more neutrophil elastase...
9.
OConallain C, Doolin M, Taggart C, Thornton F, Butler G
Mol Gen Genet
. 1999 Oct;
262(2):275-82.
PMID: 10517323
The yeast transcription factor Ace2p regulates expression of the chitinase gene CTS1 in a cell cycle-dependent manner. Nuclear localisation of Ace2p is restricted to late M and early G phases...
10.
Taggart C, Gibney J, Owens D, Collins P, Johnson A, Tomkin G
Diabet Med
. 1998 Feb;
14(12):1051-8.
PMID: 9455933
The atherogenicity of intestinally derived postprandial lipoproteins has been confirmed in a number of recent studies. We have shown abnormalities in postprandial lipoprotein metabolism in diabetic patients, a group with...