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C T Wild

Explore the profile of C T Wild including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 1008
Followers 0
Related Specialties
Science
Cell Biology
Top 10 Co-Authors
C D Weiss
T J Matthews
T K Greenwell
D C Shugars
S Wang
Y Lian
A Fong
R Vassell
J Ulmer
J Blanchard
Published In
J Virol
Proc Natl Acad Sci U S A
Nat Struct Biol
Affiliations
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Recent Articles
1.
PA-457: a potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing
Li F, Goila-Gaur R, Salzwedel K, Kilgore N, Reddick M, Matallana C, et al.
Proc Natl Acad Sci U S A . 2003 Oct; 100(23):13555-60. PMID: 14573704
New HIV therapies are urgently needed to address the growing problem of drug resistance. In this article, we characterize the anti-HIV drug candidate 3-O-(3',3'-dimethylsuccinyl) betulinic acid (PA-457). We show that...
2.
Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein
de Rosny E, Vassell R, Wingfield P, Wild C, Weiss C
J Virol . 2001 Aug; 75(18):8859-63. PMID: 11507232
Two heptad repeat regions in the ectodomain of the human immunodeficiency virus type 1 (HIV-1) transmembrane subunit (gp41) self-assemble into a six-helix bundle structure that is critical for virus entry....
3.
The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region
Barnett S, Lu S, Srivastava I, Cherpelis S, Gettie A, Blanchard J, et al.
J Virol . 2001 May; 75(12):5526-40. PMID: 11356960
Partial deletion of the second hypervariable region from the envelope of the primary-like SF162 virus increases the exposure of certain neutralization epitopes and renders the virus, SF162DeltaV2, highly susceptible to...
4.
Capture of an early fusion-active conformation of HIV-1 gp41
Furuta R, Wild C, Weng Y, Weiss C
Nat Struct Biol . 1998 Apr; 5(4):276-9. PMID: 9546217
Using an inhibitory synthetic peptide (DP-178) from HIV-1 gp41, we have trapped HIV-1 envelope glycoprotein (Env) undergoing conformational changes during virus entry. Our data show that DP-178 binds gp41 and...
5.
Biophysical characterization of recombinant proteins expressing the leucine zipper-like domain of the human immunodeficiency virus type 1 transmembrane protein gp41
Shugars D, Wild C, Greenwell T, Matthews T
J Virol . 1996 May; 70(5):2982-91. PMID: 8627774
Envelope oligomerization is thought to serve several crucial functions during the life cycle of human immunodeficiency virus type 1 (HIV-1). We recently reported that virus entry requires coiled-coil formation of...
6.
Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
Wild C, Shugars D, Greenwell T, McDanal C, Matthews T
Proc Natl Acad Sci U S A . 1994 Oct; 91(21):9770-4. PMID: 7937889
To define the role of the human immunodeficiency virus type 1 (HIV-1) envelope proteins in virus infection, a series of peptides were synthesized based on various regions of the HIV-1...