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C Simerly

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Articles 61
Citations 1436
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Recent Articles
1.
Simerly C, Castro C, Hartnett C, Lin C, Sukhwani M, Orwig K, et al.
Sci Rep . 2016 Aug; 6:31816. PMID: 27534805
The fertilizing sperm's lengthiest unchartered voyage is through the longest, least-investigated organ in a man's body - the Epididymis. Over six meters long in men, ~80 meters in stallions and...
2.
Dominko T, Ramalho-Santos J, Chan A, Moreno R, Luetjens C, Simerly C, et al.
Cloning . 2005 Oct; 1(3):143-52. PMID: 16218813
In order to optimize each of the individual steps in the nuclear transfer procedure, we report alternative protocols useful for producing recipient cytoplasts and for improving the success rate of...
3.
Terada Y, Nakamura S, Morita J, Simerly C, Hewitson L, Murakami T, et al.
Arch Androl . 2003 May; 49(3):169-77. PMID: 12746095
To describe the importance of molecular and cellular analyses in intracytoplasmic sperm injection (ICSI) the authors review the literature on biological challenges in ICSI and associated techniques. Several matters can...
4.
Balczon R, Simerly C, Takahashi D, Schatten G
Cell Motil Cytoskeleton . 2002 Jul; 52(3):183-92. PMID: 12112146
To investigate the function of the centrosome protein PCM-1, antibodies against PCM-1 were microinjected into either germinal vesicle stage meiotic oocytes or fertilized mouse eggs, and cell cycle progression events...
5.
Dominko T, Hewitson L, Simerly C, Schatten G
Ital J Anat Embryol . 2001 Dec; 106(2 Suppl 2):51-60. PMID: 11732596
Fertilization in humans follows a complex series of events including binding of the sperm to the oocyte plasma membrane, oocyte activation, the completion of meiotic maturation of the oocyte with...
6.
Chan A, Chong K, Takahashi D, Martinovich C, Duncan N, Hewitson L, et al.
Trends Pharmacol Sci . 2001 May; 22(5):214-5. PMID: 11339959
No abstract available.
7.
Hewitson L, Simerly C, Schatten G
Semin Reprod Med . 2001 Mar; 18(2):151-9. PMID: 11256165
During mammalian fertilization, the zygotic centrosome organizes a large sperm aster, critical for uniting the male and female pronuclei prior to first mitosis. Fluorescent imaging of inseminated human oocytes has...
8.
Chan A, Chong K, Martinovich C, Simerly C, Schatten G
Science . 2001 Feb; 291(5502):309-12. PMID: 11209082
Transgenic rhesus monkeys carrying the green fluorescent protein (GFP) gene were produced by injecting pseudotyped replication-defective retroviral vector into the perivitelline space of 224 mature rhesus oocytes, later fertilized by...
9.
Ramalho-Santos J, Sutovsky P, Simerly C, Oko R, Wessel G, Hewitson L, et al.
Hum Reprod . 2000 Dec; 15(12):2610-20. PMID: 11098035
We have dissected the initial stages of fertilization by intracytoplasmic sperm injection of single spermatozoa into prime oocytes from fertile rhesus monkeys (Macaca mulatta). DNA decondensation was delayed at the...
10.
Manandhar G, Moreno R, Simerly C, Toshimori K, Schatten G
J Cell Sci . 2000 Nov; 113 Pt 23:4275-86. PMID: 11069772
Mouse male meiotic cytokinesis was studied using immunofluorescent probes against various elements of cytokinetic apparatus and electron microscopy. In normal mice, some spermatocytes fail to undergo cytokinesis after meiotic I...