C Scott Swindle
Overview
Explore the profile of C Scott Swindle including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
207
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0
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Recent Articles
1.
Gu Y, Jones A, Yang W, Liu S, Dai Q, Liu Y, et al.
Proc Natl Acad Sci U S A
. 2015 Dec;
113(1):E51-60.
PMID: 26699484
Epigenetic mechanisms play important regulatory roles in hematopoiesis and hematopoietic stem cell (HSC) function. Subunits of polycomb repressive complex 1 (PRC1), the major histone H2A ubiquitin ligase, are critical for...
2.
Chewning J, Zhang W, Randolph D, Swindle C, Schoeb T, Weaver C
Biol Blood Marrow Transplant
. 2013 Mar;
19(6):876-87.
PMID: 23523972
Bone marrow graft failure and poor graft function are frequent complications after hematopoietic stem cell transplantation and result in significant morbidity and mortality. Both conditions are associated with graft-versus-host disease...
3.
Kim H, Kojima K, Swindle C, Cotta C, Huo Y, Reddy V, et al.
Blood
. 2007 Oct;
111(3):1567-74.
PMID: 17967943
The inversion of chromosome 16 in the inv(16)(p13q22) is one of the most frequent cytogenetic abnormalities observed in acute myeloid leukemia (AML). The inv(16) fuses the core binding factor (CBF)...
4.
Zhang Z, Swindle C, Bates J, Ko R, Cotta C, Klug C
Blood
. 2006 Nov;
109(5):2190-7.
PMID: 17110463
Helios is a zinc-finger protein belonging to the Ikaros family of transcriptional regulators. It is expressed, along with Ikaros, throughout early stages of thymocyte development where it quantitatively associates with...
5.
Kim H, de Guzman C, Swindle C, Cotta C, Gartland L, Scott E, et al.
Blood
. 2004 Aug;
104(13):3894-900.
PMID: 15328162
PU.1 is a member of the ETS family of transcription factors and is required for the development of multiple hematopoietic lineages. PU.1(-/-) mice die from hematopoietic failure at about embryonic...
6.
Witt C, Hurez V, Swindle C, Hamada Y, Klug C
Mol Cell Biol
. 2003 Nov;
23(23):8637-50.
PMID: 14612407
Although studies have shown that the Notch2 family member is critical for embryonic development, little is known concerning its role in hematopoiesis. In this study, we show that the effects...
7.
Swindle C, Kim H, Klug C
J Biol Chem
. 2003 Oct;
279(1):34-41.
PMID: 14559924
Although DNA methylation and transcriptional repression are generally associated, a causal role for DNA methylation in silencing of retroviral vectors has not been established. The newer generation murine stem cell...
8.
Swindle C, Klug C
J Hematother Stem Cell Res
. 2002 Aug;
11(3):449-56.
PMID: 12183830
The propensity of retroviruses toward transcriptional silencing limits their value as gene therapy vectors. Silencing has been shown to be particularly robust when stem cells are used for transduction, posing...