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C Scheidereit

Explore the profile of C Scheidereit including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 56
Citations 3532
Followers 0
Related Specialties
Molecular Biology
Cell Biology
Science
Top 10 Co-Authors
D Krappmann
E N Hatada
M Beato
F G Wulczyn
B Dorken
V Heissmeyer
M Naumann
H M Westphal
R G Roeder
F Emmerich
Published In
Mol Cell Biol
EMBO J
Nature
Proc Natl Acad Sci U S A
Cell
Affiliations
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Recent Articles
1.
High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis
Weichert W, Boehm M, Gekeler V, Bahra M, Langrehr J, Neuhaus P, et al.
Br J Cancer . 2007 Jul; 97(4):523-30. PMID: 17622249
Activation of nuclear factor-kappaB (NF-kappaB) signaling was observed in pancreatic adenocarcinoma cell lines and tumours. However, information on the expression of RelA/p65, the major transcription activating NF-kappaB subunit, in these...
2.
The pathogenetic significance of deregulated signal transduction pathways in Hodgkin's disease: the NF-kappaB-AP-1 network
Scheidereit C
Verh Dtsch Ges Pathol . 2006 Aug; 87:79-89. PMID: 16888898
In the recent years, progress has been made in defining the lineage origin of malignant cells of Hodgkin's disease. The use of single cell PCR analysis and of other molecular...
3.
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices
Schmidt-Ullrich R, Aebischer T, Hulsken J, Birchmeier W, Klemm U, Scheidereit C
Development . 2001 Oct; 128(19):3843-53. PMID: 11585809
NF-kappaB/Rel transcription factors and IkappaB kinases (IKK) are essential for inflammation and immune responses, but also for bone-morphogenesis, skin proliferation and differentiation. Determining their other functions has previously been impossible,...
4.
B-cell receptor- and phorbol ester-induced NF-kappaB and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C's
Krappmann D, Patke A, Heissmeyer V, Scheidereit C
Mol Cell Biol . 2001 Sep; 21(19):6640-50. PMID: 11533251
Antigen receptor signaling is known to activate NF-kappaB in lymphocytes. While T-cell-receptor-induced NF-kappaB activation critically depends on novel protein kinase C theta (PKCtheta), the role of novel PKCs in B-cell...
5.
Aspirin inhibits NF-kappaB and protects from angiotensin II-induced organ damage
Muller D, Heissmeyer V, Dechend R, Hampich F, Park J, Fiebeler A, et al.
FASEB J . 2001 Aug; 15(10):1822-4. PMID: 11481242
No abstract available.
6.
In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity
Wuchter C, Krappmann D, Cai Z, Ruppert V, Scheidereit C, Dorken B, et al.
Leukemia . 2001 Jun; 15(6):921-8. PMID: 11417478
The TNF-related apoptosis-inducing ligand (TRAIL) is currently under evaluation as a possible (co-)therapeutic in cancer treatment. We therefore examined 129 cell samples from patients with de novo acute leukemia as...
7.
Constitutive NF-kappaB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells
Hinz M, Loser P, Mathas S, Krappmann D, Dorken B, Scheidereit C
Blood . 2001 Apr; 97(9):2798-807. PMID: 11313274
Constitutively activated nuclear factor (NF)-kappaB is observed in a variety of neoplastic diseases and is a hallmark of the malignant Hodgkin and Reed-Sternberg cells (H/RS) in Hodgkin lymphoma. Given the...
8.
Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia
Slaugenhaupt S, Blumenfeld A, Gill S, Leyne M, Mull J, Cuajungco M, et al.
Am J Hum Genet . 2001 Feb; 68(3):598-605. PMID: 11179008
Familial dysautonomia (FD; also known as "Riley-Day syndrome"), an Ashkenazi Jewish disorder, is the best known and most frequent of a group of congenital sensory neuropathies and is characterized by...
9.
Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha
Heissmeyer V, Krappmann D, Hatada E, Scheidereit C
Mol Cell Biol . 2001 Feb; 21(4):1024-35. PMID: 11158290
p105 (NFKB1) acts in a dual way as a cytoplasmic IkappaB molecule and as the source of the NF-kappaB p50 subunit upon processing. p105 can form various heterodimers with other...
10.
The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component
Krappmann D, Hatada E, Tegethoff S, Li J, Klippel A, Giese K, et al.
J Biol Chem . 2000 Jul; 275(38):29779-87. PMID: 10893415
A critical step in the activation of NF-kappa B is the phosphorylation of I kappa Bs by the I kappa B kinase (IKK) complex. IKK alpha and IKK beta are...