C P Walsh
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Explore the profile of C P Walsh including associated specialties, affiliations and a list of published articles.
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17
Citations
1515
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Recent Articles
1.
Hilman L, Ondicova M, Caffrey A, Clements M, Conway C, Ward M, et al.
BMC Med
. 2024 Dec;
22(1):579.
PMID: 39681839
Background: The human ZFP57 gene is a major regulator of imprinted genes, maintaining DNA methylation marks that distinguish parent-of-origin-specific alleles. DNA methylation of the gene itself has shown sensitivity to...
2.
Irwin R, Scullion C, Thursby S, Sun M, Thakur A, Hilman L, et al.
Epigenetics
. 2023 May;
18(1):2216005.
PMID: 37246786
While epigenetic mechanisms such as DNA methylation and histone modification are known to be important for gene suppression, relatively little is still understood about the interplay between these systems. The...
3.
Caffrey A, Lamers Y, Murphy M, Letourneau N, Irwin R, Pentieva K, et al.
Nutr Bull
. 2023 Feb;
48(2):267-277.
PMID: 36807740
Suboptimal status of folate and/or interrelated B vitamins (B , B and riboflavin) can perturb one-carbon metabolism and adversely affect brain development in early life and brain function in later...
4.
Desmet K, van Hoeck V, Gagne D, Fournier E, Thakur A, ODoherty A, et al.
BMC Genomics
. 2016 Dec;
17(1):1004.
PMID: 27931182
Background: Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility. Non-esterified fatty acids (NEFA) are involved...
5.
McDaid J, Loughery J, Dunne P, Boyer J, Downes C, Farber R, et al.
Br J Cancer
. 2009 Jul;
101(3):441-51.
PMID: 19623177
Background: Methylating agents such as N-methyl-N-nitrosourea (MNU) can cause cell cycle arrest and death either via caspase-dependent apoptosis or via a poly(ADP-ribose) polymerase (PARP)-dependent form of apoptosis. We wished to...
6.
Dobbin E, Corrigan P, Walsh C, Welham M, Freeburn R, Wheadon H
Leuk Res
. 2008 Mar;
32(10):1554-64.
PMID: 18355917
The leukemic oncogene Tel/PDGFRbeta, was inducibly expressed in embryonic stem (ES) cells and the phenotypic and molecular changes occurring during hematopoietic differentiation investigated. Expression of Tel/PDGFRbeta resulted in an inability...
7.
Shovlin T, Bourchis D, La Salle S, ODoherty A, Trasler J, Bestor T, et al.
Hum Reprod
. 2006 Oct;
22(2):457-67.
PMID: 17060371
Background: Dnmt3L, a member of the DNA methyltransferase 3 family, lacks enzymatic activity but is required for de-novo methylation of imprinted genes in oocytes and for transposon repression in male...
8.
Walsh C, Xu G
Curr Top Microbiol Immunol
. 2006 Mar;
301:283-315.
PMID: 16570853
Cytosine methylation is a common form of post-replicative DNA modification seen in both bacteria and eukaryotes. Modified cytosines have long been known to act as hotspots for mutations due to...
9.
Lees-Murdock D, De Felici M, Walsh C
Genomics
. 2003 Jul;
82(2):230-7.
PMID: 12837272
Repetitive DNA elements account for a substantial fraction of the mammalian genome. Many are subject to DNA methylation, which is known to undergo dynamic change during mouse germ cell development....
10.
Walsh C, Vemulapalli R, Sriranganathan N, Zajac A, Jenkins M, Lindsay D
Int J Parasitol
. 2001 Feb;
31(3):253-8.
PMID: 11226451
Neospora hughesi is a recently described apicomplexan parasite that has been associated with several cases of equine protozoal myeloencephalitis. The biology of this new parasite is just beginning to be...