C P Quarterman
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Explore the profile of C P Quarterman including associated specialties, affiliations and a list of published articles.
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17
Citations
360
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Recent Articles
1.
Newlands E, Blackledge G, Slack J, Rustin G, Smith D, Stuart N, et al.
Br J Cancer
. 1992 Feb;
65(2):287-91.
PMID: 1739631
Temozolomide (CCRG 81045: M&B 39831: NSC 362856) is an analogue of mitozolomide displaying similar broad spectrum activity in mouse tumours, but showing considerably less myelosuppression in the toxicology screen. Temozolomide...
2.
Tsang L, Quarterman C, Gescher A, Slack J
Cancer Chemother Pharmacol
. 1991 Jan;
27(5):342-6.
PMID: 1998993
The present study tested the hypothesis that the experimental antineoplastic imidazotetrazinone temozolomide degrades in the biophase to 3-methyl-(triazen-1-yl)imidazole-4-carboxamide (MTIC) and exerts its cytotoxicity via this species. MTIC is a metabolite...
3.
Horspool K, Quarterman C, Slack J, Gescher A, Stevens M, Lunt E
Cancer Res
. 1989 Sep;
49(18):5023-6.
PMID: 2766272
The in vitro cytotoxicity, stability, and metabolism of the 8-(N,N-dimethylcarboxamide) and 8-(N-methylcarboxamide) analogues of the experimental antitumor drug mitozolomide have been investigated in conjunction with their in vivo murine pharmacokinetics...
4.
Kendall M, JACK D, Quarterman C, Smith S, Zaman R
Br J Clin Pharmacol
. 1984 Jan;
17 Suppl 1:87S-89S.
PMID: 6146344
Higher AUC and Cmax values were obtained for metoprolol, oxprenolol and propranolol in groups receiving the low-dose oestrogen-ethinyl oestradiol oral contraceptive, but statistical significance was reached only with metoprolol AUC....
5.
JACK D, Wilkins M, Quarterman C
Br J Clin Pharmacol
. 1983 Aug;
16(2):188-90.
PMID: 6615692
The claim for polymorphism in the metabolism of metoprolol is based on a logical fallacy. A frequency distribution of metoprolol AUC data is presented and, although highly skewed, no evidence...
6.
Kendall M, Quarterman C, JACK D, Beeley L
Br J Clin Pharmacol
. 1982 Jul;
14(1):120-2.
PMID: 7104164
No abstract available.
7.
Kendall M, Quarterman C
Int J Clin Pharmacol Ther Toxicol
. 1982 Mar;
20(3):101-4.
PMID: 7068281
The pharmacokinetics of oxprenolol have been studied in young and healthy elderly volunteers. Drug concentrations in plasma and urine have been measured after a single 80-mg dose of oxprenolol and...
8.
Kendall M, JACK D, Woods K, Laugher S, Quarterman C, John V
Br J Clin Pharmacol
. 1982 Mar;
13(3):393-8.
PMID: 7059440
1 A new osmotic pressure mediated delivery system for metoprolol (Lopresor Oros) has been evaluated by measuring the haemodynamic effects and pharmacokinetics after single and multiple oral dosing in young...
9.
JACK D, Quarterman C, Zaman R, Kendall M
Eur J Clin Pharmacol
. 1982 Jan;
23(1):37-42.
PMID: 6127220
Plasma concentrations of metoprolol, propranolol oxprenolol, acebutolol and its metabolite diacetolol were measured after single oral doses in young health volunteers. In order to assessed the inter- and intra-subject variability...
10.
Kendall M, Lambert L, Quarterman C, John V
J Clin Hosp Pharm
. 1981 Dec;
6(4):259-65.
PMID: 7338557
Beta adrenoceptor blocking drugs and diuretics are frequently given together to control hypertension and increasingly the two agents are being combined in a single preparation. Possible interactions between the two...