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C Ohlen

Explore the profile of C Ohlen including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 31
Citations 1338
Followers 0
Related Specialties
Allergy & Immunology
Science
General Medicine
Top 10 Co-Authors
K Karre
H G Ljunggren
P Hoglund
G Klein
L Franksson
J Bastin
A Townsend
R Glas
E S Huseby
T Yamasaki
Published In
J Exp Med
J Immunol
Nature
Eur J Immunol
Int J Cancer
Affiliations
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Recent Articles
1.
Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge
Doria-Rose N, Ohlen C, Polacino P, Pierce C, Hensel M, Kuller L, et al.
J Virol . 2003 Oct; 77(21):11563-77. PMID: 14557642
We evaluated four priming-boosting vaccine regimens for the highly pathogenic simian human immunodeficiency virus SHIV89.6P in Macaca nemestrina. Each regimen included gene gun delivery of a DNA vaccine expressing all...
2.
A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis
Huseby E, Liggitt D, Brabb T, Schnabel B, Ohlen C, Goverman J
J Exp Med . 2001 Sep; 194(5):669-76. PMID: 11535634
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) characterized by plaques of infiltrating CD4(+) and CD8(+) T cells. Studies of MS and experimental autoimmune encephalomyelitis...
3.
Expression of a tolerizing tumor antigen in peripheral tissue does not preclude recovery of high-affinity CD8+ T cells or CTL immunotherapy of tumors expressing the antigen
Ohlen C, Kalos M, Hong D, Shur A, Greenberg P
J Immunol . 2001 Feb; 166(4):2863-70. PMID: 11160355
Transgenic (TG) mice were generated selectively expressing the gag protein of Friend murine leukemia virus (FMuLV) in the liver. FMuLV(gag) is also expressed by the FBL leukemia, and is the...
4.
Dendritic cells lose ability to present protein antigen after stimulating antigen-specific T cell responses, despite upregulation of MHC class II expression
Bernhard H, Huseby E, Hand S, Lohmann M, Batten W, Disis M, et al.
Immunobiology . 2000 Jun; 201(5):568-82. PMID: 10834314
Immature dendritic cells (DC) take up, process and present protein antigens; mature DC are specialized for stimulating primary T cell responses with increased expression of MHC class II and co-stimulatory...
5.
Recruitment and activation of natural killer (NK) cells in vivo determined by the target cell phenotype. An adaptive component of NK cell-mediated responses
Glas R, Franksson L, Une C, Eloranta M, Ohlen C, Orn A, et al.
J Exp Med . 2000 Jan; 191(1):129-38. PMID: 10620611
Natural killer (NK) cells can spontaneously lyse certain virally infected and transformed cells. However, early in immune responses NK cells are further activated and recruited to tissue sites where they...
6.
Cutting edge: myelin basic protein-specific cytotoxic T cell tolerance is maintained in vivo by a single dominant epitope in H-2k mice
Huseby E, Ohlen C, Goverman J
J Immunol . 1999 Jul; 163(3):1115-8. PMID: 10415003
Multiple sclerosis (MS) is believed to be an autoimmune disease mediated by T cells specific for CNS Ags. MS lesions contain both CD4+ and CD8+ T lymphocytes. The contribution of...
7.
Genetic modification of T-cell clones for therapy of human viral and malignant diseases
Greenberg P, Finch R, GAVIN M, Kalos M, Lewinsohn D, Lonergan M, et al.
Cancer J Sci Am . 1998 Jun; 4 Suppl 1:S100-5. PMID: 9619278
No abstract available.
8.
Host MHC class I gene control of NK-cell specificity in the mouse
Hoglund P, Sundback J, Johansson M, Salcedo M, Ohlen C, Ljunggren H, et al.
Immunol Rev . 1997 Feb; 155:11-28. PMID: 9059879
The missing self model predicts that NK cells adapt somatically to the type as well as levels of MHC class I products expressed by their host. Transgenic and gene knock-out...
9.
Inhibition of natural killer cell-mediated bone marrow graft rejection by allogeneic major histocompatibility complex class I, but not class II molecules
Ohlen C, Hoglund P, Sentman C, Carbone E, Ljunggren H, Koller B, et al.
Eur J Immunol . 1995 May; 25(5):1286-91. PMID: 7774631
The role of major histocompatibility complex (MHC) class I and class II molecules in natural killer (NK) cell-mediated rejection of allogeneic, semisyngeneic and MHC-matched bone marrow grafts was investigated. The...
10.
Source of unique tumour antigens
Townsend A, Ohlen C, Rogers M, Edwards J, Mukherjee S, Bastin J
Nature . 1994 Oct; 371(6499):662. PMID: 7935811
No abstract available.