C M Stein
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Explore the profile of C M Stein including associated specialties, affiliations and a list of published articles.
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Articles
123
Citations
3304
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Recent Articles
1.
Carranza-Leon D, Oeser A, Marton A, Wang P, Gore J, Titze J, et al.
Lupus
. 2020 Feb;
29(5):455-462.
PMID: 32070186
Objectives: Sodium (Na) is stored in the skin and muscle and plays an important role in immune regulation. In animal models, increased tissue Na is associated with activation of the...
2.
Reese T, Dickson A, Shuey M, Gandelman J, Barnado A, Barker K, et al.
Lupus
. 2019 Jun;
28(8):954-960.
PMID: 31221051
Background: Blood pressure visit-to-visit variability is a novel risk factor for deleterious long-term cardiac and renal outcomes in the general population. We hypothesized that patients with systemic lupus erythematosus (SLE)...
3.
Mekonnen E, Bekele E, Stein C
Glob Health Epidemiol Genom
. 2018 Jun;
3:e1.
PMID: 29868226
Background: Infection by () is a necessary but not sufficient cause for tuberculosis (TB). Although numerous studies suggest human genetic variation may influence TB pathogenesis, there is a conspicuous lack...
4.
Kawai V, Levinson R, Adefurin A, Kurnik D, Collier S, Conway D, et al.
Clin Endocrinol (Oxf)
. 2017 Apr;
87(2):149-155.
PMID: 28429832
Objective: Gestational diabetes (GDM) is characterized by maternal glucose intolerance that manifests during pregnancy. Because GDM resembles type 2 diabetes (T2DM), shared genetic predisposition is likely but has not been...
5.
Johnson J, Caudle K, Gong L, Whirl-Carrillo M, Stein C, Scott S, et al.
Clin Pharmacol Ther
. 2017 Feb;
102(3):397-404.
PMID: 28198005
This document is an update to the 2011 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2C9 and VKORC1 genotypes and warfarin dosing. Evidence from the published literature is presented for...
6.
Adefurin A, Ghimire L, Kohli U, Muszkat M, Sofowora G, Li C, et al.
Pharmacogenomics J
. 2016 Apr;
17(4):366-371.
PMID: 27089938
The alpha (α)-adrenergic receptors contribute to vasoconstriction in humans. We tested the hypothesis that variation in the ADRA1B gene contributes to interindividual variability and ethnic differences in adrenergic vasoconstriction. We...
7.
Barnado A, Oeser A, Zhang Y, Okafor C, Titze J, Stein C, et al.
Lupus
. 2016 Apr;
25(13):1463-1469.
PMID: 27055519
Sodium and potassium intake are modifiable determinants of hypertension in the general population but have not been studied in patients with systemic lupus erythematosus (SLE). We examined the relationship between...
8.
Feng Q, Wei W, Chung C, Levinson R, Bastarache L, Denny J, et al.
Pharmacogenomics J
. 2016 Feb;
17(2):204-208.
PMID: 26902539
Statins (HMG-CoA reductase inhibitors) lower low-density lipoprotein cholesterol (LDL-C) and prevent cardiovascular disease. However, there is wide individual variation in LDL-C response. Drugs targeting proprotein convertase subtilin/kexin type 9 (PCSK9)...
9.
Chung C, Ormseth M, Connelly M, Oeser A, Solus J, Otvos J, et al.
Lupus
. 2015 Dec;
25(3):296-300.
PMID: 26637290
Background: GlycA is a novel marker of systemic inflammation detected by nuclear magnetic resonance (NMR) spectroscopy. In the general population, GlycA is correlated with inflammatory markers such as C-reactive protein...
10.
Birdwell K, Decker B, Barbarino J, Peterson J, Stein C, Sadee W, et al.
Clin Pharmacol Ther
. 2015 Mar;
98(1):19-24.
PMID: 25801146
Tacrolimus is the mainstay immunosuppressant drug used after solid organ and hematopoietic stem cell transplantation. Individuals who express CYP3A5 (extensive and intermediate metabolizers) generally have decreased dose-adjusted trough concentrations of...