C M Posavad
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Explore the profile of C M Posavad including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
387
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Recent Articles
1.
Posavad C, Zhao L, Dong L, Jin L, Stevens C, Magaret A, et al.
Mucosal Immunol
. 2017 Jan;
10(5):1259-1269.
PMID: 28051084
Local mucosal cellular immunity is critical in providing protection from HSV-2. To characterize and quantify HSV-2-reactive mucosal T cells, lymphocytes were isolated from endocervical cytobrush and biopsy specimens from 17...
2.
Posavad C, Zhao L, Mueller D, Stevens C, Huang M, Wald A, et al.
Mucosal Immunol
. 2014 Jun;
8(1):115-26.
PMID: 24917455
Relatively little is known about the human T-cell response to herpes simplex virus type 2 (HSV-2) in the female genital tract, a major site of heterosexual HSV-2 acquisition, transmission, and...
3.
Posavad C, Huang M, Barcy S, Koelle D, Corey L
J Immunol
. 2000 Jul;
165(2):1146-52.
PMID: 10878394
Herpes simplex virus (HSV) establishes a lifelong infection in humans. Reactivation of latent virus occurs intermittently so that the immune system is frequently exposed to viral Ag, providing an opportunity...
4.
Koelle D, Posavad C, Barnum G, Johnson M, Frank J, Corey L
J Clin Invest
. 1998 Apr;
101(7):1500-8.
PMID: 9525993
The mechanisms involved in host clearance of symptomatic mucocutaneous herpes simplex virus (HSV) infection are unclear. We studied the functional properties of bulk cultures of skin-infiltrating lymphocytes from normal skin...
5.
6.
Swetter S, Hill E, Kern E, Koelle D, Posavad C, Lawrence W, et al.
J Infect Dis
. 1998 Mar;
177(3):543-50.
PMID: 9498430
A 34-year-old healthy woman presented with a 15-month history of persistent, nonhealing vulvar ulcerations due to herpes simplex virus (HSV) type 2. Extensive dermatologic workup and serial skin biopsies failed...
7.
Posavad C, Koelle D, Shaughnessy M, Corey L
Proc Natl Acad Sci U S A
. 1997 Sep;
94(19):10289-94.
PMID: 9294203
The specific mechanisms underlying the varied susceptibility of HIV-infected (HIV+) individuals to opportunistic infections (OI) are still incompletely understood. One hypothesis is that quantitative differences in specific T cell responses...
8.
Posavad C, Koelle D, Corey L
J Virol
. 1996 Nov;
70(11):8165-8.
PMID: 8892947
Herpes simplex virus (HSV)-specific CD8+ cytotoxic T lymphocytes (CTL) have rarely been detected in humans, presumably because of virus-induced mechanisms that downregulate major histocompatibility complex class I expression. We have...
9.
Posavad C, NEWTON J, Rosenthal K
J Virol
. 1994 Jun;
68(6):4072-4.
PMID: 8189546
The effect of herpes simplex virus type 1 (HSV-1) infection on human cytotoxic T-lymphocyte (CTL) lytic function was assessed. All HSV-infected CTL populations tested were significantly inhibited in lysing target...
10.
Posavad C, NEWTON J, Rosenthal K
J Immunol
. 1993 Nov;
151(9):4865-73.
PMID: 8409445
Previously, we demonstrated that human anti-HSV CTL and allo-antigen-specific CTL were inhibited in lysing their normally sensitive target cells when they were exposed to human fibroblasts (FB) infected with herpes...