C M Loughrey
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Explore the profile of C M Loughrey including associated specialties, affiliations and a list of published articles.
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20
Citations
231
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Recent Articles
1.
Kelly A, Elliott E, Matsuda R, Kaneko N, Smith G, Loughrey C
Br J Pharmacol
. 2011 Jun;
165(4b):1068-83.
PMID: 21658026
Background And Purpose: Reduced cardiac contractility has been associated with disrupted myocardial Ca(2+) signalling. The 1,4 benzothiazepine K201 (JTV-519) acts on several Ca(2+) handling proteins and improves cardiac contractility in...
2.
Quinn C, Lockhart C, Hamilton P, Loughrey C, McVeigh G
Diabetes Obes Metab
. 2010 Jul;
12(8):709-15.
PMID: 20590748
Aim: Flow-mediated dilation (FMD) is a surrogate marker of endothelial function, which has been proposed as a barometer of vascular health. Impaired microvascular response to reactive hyperaemia is thought to...
3.
Fitzpatrick A, Loughrey C, Johnston P, McKee S, Spence W, Flynn P, et al.
Eur J Neurol
. 2008 Feb;
15(3):e21-2.
PMID: 18290840
No abstract available.
4.
Loughrey C, Otani N, Seidler T, Craig M, Matsuda R, Kaneko N, et al.
Cardiovasc Res
. 2007 Jul;
76(2):236-46.
PMID: 17644079
Objectives: The drug K201 (JTV-519) increases inotropy and suppresses arrhythmias in failing hearts, but the effects of K201 on normal hearts is unknown. Methods: The effect of K201 on excitation-contraction...
5.
Loughrey C, Preece M, Green A
J Clin Pathol
. 2004 Dec;
58(1):20-1.
PMID: 15623476
No abstract available.
6.
Loughrey C, Smith G, MacEachern K
Am J Physiol Heart Circ Physiol
. 2004 May;
287(3):H1149-59.
PMID: 15117716
Both the cardiac action potential duration (APD) (0.6-1 s) and resting heart rate (30-40 beats/min) in the horse are significantly different from humans and smaller mammals, including the rabbit. This...
7.
Wokosin D, Loughrey C, Smith G
Biophys J
. 2004 Mar;
86(3):1726-38.
PMID: 14990500
Two-photon excitation (TPE) spectra of Fura-2, -4F, -6F, -FF, and Furaptra were characterized using a tunable (750-850 nM) ultra-short pulse laser. Two-photon fluorescence of these dyes was studied in free...
8.
Loughrey C, Seidler T, Miller S, Prestle J, MacEachern K, REYNOLDS D, et al.
J Physiol
. 2004 Feb;
556(Pt 3):919-34.
PMID: 14966299
This study investigated the function of FK506-binding protein (FKBP12.6) using adenoviral-mediated gene transfer to over-express FKBP12.6 (Ad-FKBP12.6) in adult rabbit ventricular cardiomyocytes. Infection with a beta-galactosidase-expressing adenovirus (Ad-LacZ) was used...
9.
Loughrey M, Loughrey C, Johnston S, ORourke D
Forensic Sci Int
. 2003 Jul;
134(2-3):232-3.
PMID: 12850423
A case of fatal overdose of tramadol is described, occurring in a 67-year-old man with painful rib fractures who accidentally ingested more than the recommended daily dose. The mode of...
10.
Loughrey C, MacEachern K, Cooper J, Smith G
Cell Calcium
. 2003 May;
34(1):1-9.
PMID: 12767887
The Ca(2+) dissociation constant (K(d)) of Fluo-3 was determined using confocal fluorescence microscopy in two different situations: (i) within the cytosol of a permeabilised cardiomyocyte; and (ii) in an intact...