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C M Chase

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Articles 23
Citations 538
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Recent Articles
1.
Shinoda K, Akiyoshi T, Chase C, Farkash E, Ndishabandi D, Raczek C, et al.
Am J Transplant . 2014 Aug; 14(10):2263-2274. PMID: 25155089
The relative contribution of central and peripheral mechanisms to the generation and maintenance of allograft tolerance is of considerable interest. Here, we present new evidence that regulatory T cells (Foxp3(+)...
2.
Hirohashi T, Chase C, Pelle P, Sebastian D, Alessandrini A, Madsen J, et al.
Am J Transplant . 2011 Nov; 12(2):313-21. PMID: 22070565
Chronic allograft vasculopathy (CAV) in murine heart allografts can be elicited by adoptive transfer of donor specific antibody (DSA) to class I MHC antigens and is independent of complement. Here...
3.
Hirohashi T, Uehara S, Chase C, DellaPelle P, Madsen J, Russell P, et al.
Am J Transplant . 2010 Jan; 10(3):510-7. PMID: 20055805
Complement fixation, as evidenced by C4d in the microvasculature, is a widely accepted criterion of antibody-mediated rejection. Complement fixation has been shown to be essential in acute antibody-mediated rejection, but...
4.
Graham J, Wilkinson R, Hirohashi T, Chase C, Colvin R, Madsen J, et al.
Am J Transplant . 2009 Oct; 9(11):2479-84. PMID: 19843029
Viral infections including those due to cytomegalovirus have been associated with accelerated cardiac allograft vasculopathy (CAV) in clinical trials and some animal models. Evidence demonstrating a direct causal relationship between...
5.
Kitchens W, Chase C, Uehara S, Cornell L, Colvin R, Russell P, et al.
Am J Transplant . 2007 Oct; 7(12):2675-82. PMID: 17924996
Cardiac allograft vasculopathy (CAV) is a major source of late posttransplant mortality. Although numerous cell types are implicated in the pathogenesis of CAV, it is unclear which cells actually induce...
6.
Lacy-Hulbert A, Ueno T, Ito T, Jurewicz M, Izawa A, Smith R, et al.
Am J Transplant . 2007 Mar; 7(5):1080-90. PMID: 17359504
Integrin alpha v beta 3 is important for cell survival, signaling and migration, particularly during angiogenesis and tumorigenesis, where it has been proposed as a therapeutic target. alpha v beta...
7.
Uehara S, Chase C, Cornell L, Madsen J, Russell P, Colvin R
Am J Transplant . 2007 Jan; 7(1):57-65. PMID: 17227558
Murine heterotopic cardiac allografts were used to reveal some of the fundamental interrelationships between donor-specific alloantibodies (DSA), chronic transplant arteriopathy (CTA) and capillary C4d deposition. B10.BR recipients of B10.A hearts...
8.
Uehara S, Chase C, Colvin R, Madsen J, Russell P
Transplant Proc . 2006 Dec; 38(10):3169-71. PMID: 17175214
We previously demonstrated that cardiac allografts to fully tolerant chimeric mice developed cardiac allograft vasculopathy (CAV). Here we begin to examine which components of the immune system are responsible for...
9.
Uehara S, Chase C, Colvin R, Russell P, Madsen J
Transplant Proc . 2005 Apr; 37(1):70-1. PMID: 15808550
In prior experiments, we found that recipients, even though specifically tolerant of donor antigens, will develop striking cardiac allograft vasculopathy (CAV) in allogeneic mouse heart transplants. This suggested that innate...
10.
Bracy J, Chase C, Russell P, Mauiyyedi S, Colvin R, Iacomini J
Gene Ther . 2002 Mar; 8(22):1738-44. PMID: 11892842
In order for xenotransplantation to become a clinical reality, and fulfill its promise of overcoming shortages of human organs and tissues, rejection mediated by the host's immune system must first...