C Lopez-Otin
Overview
Explore the profile of C Lopez-Otin including associated specialties, affiliations and a list of published articles.
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Articles
166
Citations
4867
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Recent Articles
1.
Soria-Valles C, Gutierrez-Fernandez A, Guiu M, Mari B, Fueyo A, Gomis R, et al.
Oncogene
. 2019 May;
38(28):5739.
PMID: 31053808
The original microRNA hybridization data for this article, which has been available for the scientific community upon request, has now been deposited in the GEO repository under accession number GSE124432.
2.
Nadeu F, Clot G, Delgado J, Martin-Garcia D, Baumann T, Salaverria I, et al.
Leukemia
. 2017 Sep;
32(3):645-653.
PMID: 28924241
Genome studies of chronic lymphocytic leukemia (CLL) have revealed the remarkable subclonal heterogeneity of the tumors, but the clinical implications of this phenomenon are not well known. We assessed the...
3.
Lopez-Otin C, Marino G
Methods Enzymol
. 2017 Mar;
587:189-205.
PMID: 28253955
Autophagy is a catabolic pathway, which mediates the degradation of cytoplasmic components and sustains many essential cellular functions. More than 30 genes have been involved in different aspects of this...
4.
Osorio F, Soria-Valles C, Santiago-Fernandez O, Freije J, Lopez-Otin C
Int Rev Cell Mol Biol
. 2016 Aug;
326:133-74.
PMID: 27572128
NF-κB signaling exerts essential roles in immunity and cellular stress responses, regulating many functions related with organism innate defense. Besides, NF-κB altered signaling has been causally linked to ageing and...
5.
Valdes-Mas R, Gutierrez-Abril J, Puente X, Lopez-Otin C
Cell Death Differ
. 2015 Nov;
23(1):7-9.
PMID: 26611460
No abstract available.
6.
Bassaganyas L, Bea S, Escaramis G, Tornador C, Salaverria I, Zapata L, et al.
Leukemia
. 2015 Mar;
29(3):758.
PMID: 25738466
No abstract available.
7.
Galluzzi L, Bravo-San Pedro J, Vitale I, Aaronson S, Abrams J, Adam D, et al.
Cell Death Differ
. 2014 Sep;
22(1):58-73.
PMID: 25236395
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally...
8.
Queiros A, Villamor N, Clot G, Martinez-Trillos A, Kulis M, Navarro A, et al.
Leukemia
. 2014 Aug;
29(3):598-605.
PMID: 25151957
Prospective identification of patients with chronic lymphocytic leukemia (CLL) destined to progress would greatly facilitate their clinical management. Recently, whole-genome DNA methylation analyses identified three clinicobiologic CLL subgroups with an...
9.
Lopez-Guerra M, Xargay-Torrent S, Rosich L, Montraveta A, Roldan J, Matas-Cespedes A, et al.
Leukemia
. 2014 May;
29(1):96-106.
PMID: 24781018
Targeting Notch signaling has emerged as a promising therapeutic strategy for chronic lymphocytic leukemia (CLL), especially for the poor prognostic subgroup of NOTCH1-mutated patients. Here, we report that the γ-secretase...
10.
Garcia-Casado G, Sanchez-Monge R, Lopez-Otin C, Salcedo G
Theor Appl Genet
. 2013 Nov;
89(1):60-3.
PMID: 24177770
A new inhibitor of insect α-amylase, designated RDAI-1, has been purified from rye (Secale cereale L.) endosperm. RDAI-1 is homologous to wheat homodimeric inhibitors. This homology is supported by their...