C L Greer
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Explore the profile of C L Greer including associated specialties, affiliations and a list of published articles.
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20
Citations
354
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Recent Articles
1.
Peculis B, Greer C
RNA
. 1998 Dec;
4(12):1610-22.
PMID: 9848657
Accurate and efficient processing of pre-rRNA is critical to the accumulation of mature functional ribosomal subunits for maintenance of cell growth. Processing requires numerous factors which act in trans as...
2.
Rose A, Belford H, Shen W, Greer C, Hopper A, Martin N
Biochimie
. 1995 Jan;
77(1-2):45-53.
PMID: 7599275
Most steps in the maturation of nuclear coded tRNAs occur in the nucleus in eukaryotic cells, but little is known as to the intranuclear location of this RNA maturation pathway....
3.
Atkin A, Riazi M, Greer C, Roy K, Bell J
Gene
. 1993 Nov;
134(1):57-65.
PMID: 8244031
Nonsense suppressors derived from Saccharomyces cerevisiae tRNA(Trp) genes have not been identified by classical genetic screens, although one can construct efficient amber (am) suppressors from them by making the appropriate...
4.
Haselbeck R, Greer C
Biochemistry
. 1993 Aug;
32(33):8575-81.
PMID: 8357802
The presence or absence of an intron defines two classes of eukaryotic nuclear tRNA genes whose transcripts differ in a requirement for splicing. Using quantitative nuclear microinjection, we have previously...
5.
Belford H, Westaway S, Abelson J, Greer C
J Biol Chem
. 1993 Feb;
268(4):2444-50.
PMID: 8428919
We have examined multiple cofactor usage by yeast tRNA ligase in splicing in vitro. The ligase mechanism of action requires expenditure of two molar equivalents of nucleotide cofactor per mole...
6.
Westaway S, Belford H, Apostol B, Abelson J, Greer C
J Biol Chem
. 1993 Feb;
268(4):2435-43.
PMID: 8428918
Yeast tRNA ligase possesses multiple activities which are required for the joining of tRNA halves during the tRNA splicing process: cyclic phosphodiesterase, kinase, adenylylate synthetase, and ligase. A deletion polypeptide...
7.
Phizicky E, Greer C
Trends Biochem Sci
. 1993 Jan;
18(1):31-4.
PMID: 8438235
There has been a growing recognition that there are many conserved features among apparently diverse RNA splicing systems, suggesting that they may have a common origin. However, pre-tRNA splicing is...
8.
Shapero M, Greer C
Biochemistry
. 1992 Mar;
31(8):2359-67.
PMID: 1540592
A survey of exon sequence and structure requirements for splicing was undertaken using labeled pre-tRNA substrates prepared by in vitro transcription of bacterial promoter-yeast tRNA(Tyr) gene fusions. Transcription templates were...
9.
Shapero M, Greer C
Biochemistry
. 1991 Jul;
30(26):6465-75.
PMID: 1828990
Fusion of a prokaryotic promoter to a yeast tRNA gene provides a means for uncoupling analyses of mutations affecting splicing from requirements for transcription and other processing steps. For this...
10.
Apostol B, Greer C
Nucleic Acids Res
. 1991 Apr;
19(8):1853-60.
PMID: 2030966
Joining of tRNA halves during splicing in extracts of Saccharomyces cerevisiae requires each of the three enzymatic activities associated with the tRNA ligase polypeptide. Joining is most efficient for tRNA...