C K Miranti
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Explore the profile of C K Miranti including associated specialties, affiliations and a list of published articles.
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12
Citations
764
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Recent Articles
1.
Watson M, Berger P, Banerjee K, Frank S, Tang L, Ganguly S, et al.
Oncogene
. 2021 Apr;
40(18):3260-3272.
PMID: 33846571
The molecular mechanisms of luminal cell differentiation are not understood well enough to determine how differentiation goes awry during oncogenesis. Using RNA-Seq analysis, we discovered that CREB1 plays a central...
2.
Jiang L, Ivich F, Tahsin S, Tran M, Frank S, Miranti C, et al.
Biomicrofluidics
. 2019 Nov;
13(6):064116.
PMID: 31768202
The prostate is a walnut-sized gland that surrounds the urethra of males at the base of the bladder comprising a muscular portion, which controls the release of urine, and a...
3.
Meng X, Vander Ark A, Lee P, Hostetter G, Bhowmick N, Matrisian L, et al.
Oncogene
. 2015 Aug;
35(18):2370-8.
PMID: 26279296
Breast cancer (BCa) bone metastases cause osteolytic bone lesions, which result from the interactions of metastatic BCa cells with osteoclasts and osteoblasts. Osteoclasts differentiate from myeloid lineage cells. To understand...
4.
Miranti C
Cell Signal
. 2008 Sep;
21(2):196-211.
PMID: 18822372
The recent identification of metastasis suppressor genes, uniquely responsible for negatively controlling cancer metastasis, are providing inroads into the molecular machinery involved in metastasis. While the normal function of a...
5.
Sridhar S, Miranti C
Oncogene
. 2005 Dec;
25(16):2367-78.
PMID: 16331263
KAI1/CD82, a tetraspanin protein, was first identified as a metastasis suppressor in prostate cancer. How loss of CD82 expression promotes cancer metastasis is unknown. Restoration of CD82 expression to physiological...
6.
Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains
Woodside D, Obergfell A, Leng L, Wilsbacher J, Miranti C, Brugge J, et al.
Curr Biol
. 2001 Nov;
11(22):1799-804.
PMID: 11719224
Syk protein tyrosine kinase is essential for immune system development and function [1]and for the maintenance of vascular integrity [2,3]. In leukocytes, Syk is activated by binding to diphosphorylated immune...
7.
Miranti C, Ohno S, Brugge J
J Biol Chem
. 1999 Apr;
274(15):10571-81.
PMID: 10187852
Adhesion of fibroblasts to extracellular matrices via integrin receptors is accompanied by extensive cytoskeletal rearrangements and intracellular signaling events. The protein kinase C (PKC) family of serine/threonine kinases has been...
8.
Miranti C, Leng L, Maschberger P, Brugge J, Shattil S
Curr Biol
. 1998 Dec;
8(24):1289-99.
PMID: 9843681
Background: . Integrins induce the formation of large complexes of cytoskeletal and signaling proteins, which regulate many intracellular processes. The activation and assembly of signaling complexes involving focal adhesion kinase...
9.
Xia Z, Dudek H, Miranti C, Greenberg M
J Neurosci
. 1996 Sep;
16(17):5425-36.
PMID: 8757255
The regulation of gene expression by neurotransmitters is likely to play a key role in neuroplasticity both during development and in the adult animal. Therefore, it is important to determine...
10.
Miranti C, Ginty D, Huang G, Chatila T, Greenberg M
Mol Cell Biol
. 1995 Jul;
15(7):3672-84.
PMID: 7791774
Enhanced levels of cytoplasmic Ca2+ due to membrane depolarization with elevated levels of KCl or exposure to the Ca2+ ionophore ionomycin stimulate serum response element (SRE)-dependent transcription in the pheochromocytoma...