C K Mirabelli
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Explore the profile of C K Mirabelli including associated specialties, affiliations and a list of published articles.
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Articles
74
Citations
1006
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Recent Articles
1.
Newman W, Mirabelli C
Expert Opin Investig Drugs
. 2005 Jul;
7(1):19-25.
PMID: 15991916
Leukocytes participate in different ways in inflammatory diseases. The nature of the disease can be seen as a reflection, in part, of the migration patterns of different leukocyte types in...
2.
Hughes J, Bennett C, Cook P, Guinosso C, Mirabelli C, Juliano R
J Pharm Sci
. 1994 Apr;
83(4):597-600.
PMID: 8046622
Antisense oligonucleotides have the ability to inhibit gene expression in viral infections, malignancy, and other diseases. Even though much work has been accomplished with oligonucleotides demonstrating in vitro therapeutic effects,...
3.
Perlaky L, Saijo Y, BUSCH R, Bennett C, Mirabelli C, Crooke S, et al.
Anticancer Drug Des
. 1993 Feb;
8(1):3-14.
PMID: 8476501
The human nucleolar antigen p120 was detected with an anti-p120 monoclonal antibody (MAbp120) in most human malignant tumors (Freeman et al., Cancer Research, 48, 1244-1251, 1988). Stable transfection of the...
4.
Cowsert L, Fox M, Zon G, Mirabelli C
Antimicrob Agents Chemother
. 1993 Feb;
37(2):171-7.
PMID: 8383937
Papillomaviruses induce benign proliferative lesions, such as genital warts, in humans. The E2 gene product is thought to play a major role in the regulation of viral transcription and DNA...
5.
Bennett C, Chiang M, Chan H, Shoemaker J, Mirabelli C
Mol Pharmacol
. 1992 Jun;
41(6):1023-33.
PMID: 1352033
We have investigated the use of a cationic lipid preparation to enhance antisense oligonucleotide activity in human umbilical vein endothelial cells. A liposomal preparation containing the cationic lipid N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride...
6.
Tan K, Dorman T, Falls K, Chung T, Mirabelli C, Crooke S, et al.
Cancer Res
. 1992 Jan;
52(1):231-4.
PMID: 1309226
Human cells contain two topoisomerase II isozymes named topo II alpha and topo II beta. The complementary DNAs for both enzymes have been cloned. The topo II alpha and topo...
7.
Mirabelli C, Bennett C, Anderson K, Crooke S
Anticancer Drug Des
. 1991 Dec;
6(6):647-61.
PMID: 1663361
The use of antisense oligonucleotide as pharmacologic agents is a derivative of the central dogma of molecular biology and knowledge of the physical and chemical properties that govern the structure...
8.
Woessner R, Mattern M, Mirabelli C, Johnson R, Drake F
Cell Growth Differ
. 1991 Apr;
2(4):209-14.
PMID: 1651102
The cellular content of 170kD and 180kD topoisomerase II was studied as a function of the proliferation state and cell cycle position in NIH-3T3 cells. When the cells were synchronized...
9.
Mattern M, Nambi P, Bartus J, Mirabelli C, Crooke S, Johnson R
Receptor
. 1991 Jan;
1(3):181-90.
PMID: 1668830
Incubation of cultured rat aortic smooth muscle cells (A-10) with activators of cyclic nucleotides resulted in transiently increased activity of extractable topoisomerase I or topoisomerase II. ANF, which induces cGMP...
10.
Badger A, Schwartz D, Picker D, DORMAN J, Bradley F, Cheeseman E, et al.
J Med Chem
. 1990 Nov;
33(11):2963-70.
PMID: 2146392
Spirogermanium (1; 8,8-diethyl-N,N-dimethyl-2-aza-8- germaspiro[4.5]decane-2-propanamine dihydrochloride) is a potent cytotoxic agent in vitro which has demonstrated limited activity in experimental animal tumor models. Subsequently, it has been reported that spirogermanium has...