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C J Westmark

Explore the profile of C J Westmark including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 182
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Recent Articles
1.
Westmark C, Sokol D, Maloney B, Lahiri D
Mol Psychiatry . 2016 Aug; 21(10):1333-41. PMID: 27573877
Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and is associated with up to 5% of autism cases. Several promising drugs are in preclinical testing...
2.
Westmark C
Mol Psychiatry . 2012 Aug; 18(4):425-34. PMID: 22925831
Accumulating evidence suggests that dysregulated levels of amyloid β-protein precursor (APP) and its catabolites contribute to the impaired synaptic plasticity and seizure incidence observed in several neurological disorders, including Alzheimer's...
3.
Malter J, Ray B, Westmark P, Westmark C
Curr Alzheimer Res . 2010 Jan; 7(3):200-6. PMID: 20088809
As the mechanisms underlying neuronal development and degeneration become clarified, a number of common effectors and signaling pathways are becoming apparent. Here we describe the identification of Abeta, long considered...
4.
Westmark C, Malter J
Brain Res Mol Brain Res . 2001 Jun; 90(2):193-201. PMID: 11406297
The precise signaling pathways which contribute to amyloid precursor protein (APP) gene expression remain incompletely characterized. We evaluated the role of protein kinases, calcium and phospholipase C (PLC) in modulating...
5.
Westmark C, Malter J
J Biol Chem . 2000 Oct; 276(2):1119-26. PMID: 11042220
The signal transduction pathways regulating nucleolin mRNA and protein production have yet to be elucidated. Peripheral blood mononuclear cells treated with phorbol 12-myristate 13-acetate showed steady state levels of nucleolin...
6.
Westmark C, Ghose R, Huber P
Nucleic Acids Res . 1998 Oct; 26(20):4758-64. PMID: 9753746
Ribosomes prepared from somatic tissue of Xenopus laevis inhibit transcription by RNA polymerase III. This observation parallels an earlier report that a high speed fraction from activated egg extract, which...
7.
Rajagopalan L, Westmark C, Jarzembowski J, Malter J
Nucleic Acids Res . 1998 Jul; 26(14):3418-23. PMID: 9649628
We have previously shown that heterogeneous nuclear ribonucleoprotein C (hnRNP C) and nucleolin bound specifically to a 29 nt sequence in the 3'-untranslated region of amyloid precursor protein (APP) mRNA....