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C J Packard

Explore the profile of C J Packard including associated specialties, affiliations and a list of published articles. Areas
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Articles 234
Citations 4539
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Recent Articles
1.
Bjornson E, Packard C, Adiels M, Andersson L, Matikainen N, Soderlund S, et al.
J Intern Med . 2019 Dec; 288(4):422-438. PMID: 31846520
Background: Renewed interest in triglyceride-rich lipoproteins as causative agents in cardiovascular disease mandates further exploration of the integrated metabolism of chylomicrons and very low-density lipoproteins (VLDL). Methods: Novel tracer techniques...
2.
Bjornson E, Packard C, Taskinen M, Boren J
J Intern Med . 2019 Oct; 287(1):118. PMID: 31631432
No abstract available.
3.
Bjornson E, Packard C, Adiels M, Andersson L, Matikainen N, Soderlund S, et al.
J Intern Med . 2019 Feb; 285(5):562-577. PMID: 30779243
Background: Triglyceride-rich lipoproteins and their remnants have emerged as major risk factors for cardiovascular disease. New experimental approaches are required that permit simultaneous investigation of the dynamics of chylomicrons (CM)...
4.
Bassendine M, Nielsen S, Bridge S, Felmlee D, Sheridan D, Packard C, et al.
Clin Res Hepatol Gastroenterol . 2016 Nov; 41(1):25-30. PMID: 27840032
Hepatitis C virus (HCV) is a major pathogen with approximately 3% of the world's population (over 170 million) infected. Epidemiological studies have shown HCV is associated with an increased risk...
5.
Sattar N, Murray H, Welsh P, Blauw G, Buckley B, de Craen A, et al.
Diabetologia . 2008 Nov; 52(2):235-9. PMID: 19030842
Aims/hypothesis: The aim of this prospective study was to determine whether circulating intercellular adhesion molecule (ICAM) 1, as a potential surrogate of 'endothelial activation', is more strongly associated with risk...
6.
Barwell N, Malkova D, Moran C, Cleland S, Packard C, Zammit V, et al.
Diabetologia . 2008 Jul; 51(10):1912-9. PMID: 18663427
Aims/hypothesis: Sedentary offspring of patients with type 2 diabetes are often more insulin-resistant than persons with no family history of diabetes, but when active or fit offspring of type 2...
7.
Trompet S, de Craen A, Slagboom P, Shepherd J, Blauw G, Murphy M, et al.
Exp Gerontol . 2008 May; 43(8):801-5. PMID: 18504081
Inflammation plays a prominent role in the development of atherosclerosis, which is the most important risk factor for vascular events. Lymphotoxin-alpha (LTA) is a pro-inflammatory cytokine and is found to...
8.
Trompet S, de Craen A, Slagboom P, Shepherd J, Blauw G, Murphy M, et al.
Brain . 2008 Feb; 131(Pt 4):1069-77. PMID: 18304957
Inflammation is thought to play an important role in the development of cognitive decline and dementia in old age. The interleukin-1 signalling pathway may play a prominent role in this...
9.
Duvillard L, Caslake M, Petit J, Verges B, Gambert P, Packard C
Atherosclerosis . 2008 Jan; 199(1):27-33. PMID: 18177876
Very low density lipoprotein (VLDL) 1 and 2 were fractionated by heparin affinity chromatography into a bound and an unbound fraction and the different subfractions were quantified in 17 normolipidaemic...
10.
Trompet S, Pons D, de Craen A, Slagboom P, Shepherd J, Blauw G, et al.
Ann N Y Acad Sci . 2007 Apr; 1100:189-98. PMID: 17460178
Proinflammatory cytokines, like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), are implicated in the development of atherosclerosis. The role of anti-inflammatory cytokines, like IL-10, is largely unknown. We investigated the...