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C J Luckey

Explore the profile of C J Luckey including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 180
Followers 0
Related Specialties
Allergy & Immunology
General Medicine
Science
Top 10 Co-Authors
V H Engelhard
J Shabanowitz
D F Hunt
J A Marto
T A Colella
F M White
J D Lippolis
E L Huczko
V L Crotzer
L B Russell
Published In
J Exp Med
J Immunol
Int Immunol
Proc Natl Acad Sci U S A
Affiliations
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Recent Articles
1.
Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors
Luckey C, Marto J, Partridge M, Hall E, White F, Lippolis J, et al.
J Immunol . 2001 Jul; 167(3):1212-21. PMID: 11466336
We have studied the contributions of proteasome inhibitor-sensitive and -insensitive proteases to the generation of class I MHC-associated peptides. The cell surface expression of 13 different human class I MHC...
2.
Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65)
Nepom G, Lippolis J, White F, Masewicz S, Marto J, Herman A, et al.
Proc Natl Acad Sci U S A . 2001 Feb; 98(4):1763-8. PMID: 11172025
T cell recognition of autoantigens is critical to progressive immune-mediated destruction of islet cells, which leads to autoimmune diabetes. We identified a naturally presented autoantigen from the human islet antigen...
3.
Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: implications for tumor immunotherapy
Colella T, Bullock T, Russell L, MULLINS D, Overwijk W, Luckey C, et al.
J Exp Med . 2000 Apr; 191(7):1221-32. PMID: 10748239
The human tyrosinase-derived peptide YMDGTMSQV is presented on the surface of human histocompatibility leukocyte antigen (HLA)-A*0201(+) melanomas and has been suggested to be a tumor antigen despite the fact that...
4.
Proteasomes can either generate or destroy MHC class I epitopes: evidence for nonproteasomal epitope generation in the cytosol
Luckey C, King G, Marto J, Venketeswaran S, Maier B, Crotzer V, et al.
J Immunol . 1998 Jul; 161(1):112-21. PMID: 9647214
Proteasomes have been implicated in the production of the majority of peptides that associate with MHC class I molecules. We used two different proteasome inhibitors, the peptide aldehyde N-acetyl-L-leucyl-L-leucyl-L-norleucinal (LLnL)...
5.
The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol
Mosse C, Meadows L, Luckey C, Kittlesen D, Huczko E, Slingluff C, et al.
J Exp Med . 1998 Jan; 187(1):37-48. PMID: 9419209
Formation of major histocompatibility complex class I-associated peptides from membrane proteins has not been thoroughly investigated. We examined the processing of an HLA-A*0201-associated epitope, YMDGTMSQV, that is derived from the...
6.
Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice
Man S, Newberg M, Crotzer V, Luckey C, Williams N, Chen Y, et al.
Int Immunol . 1995 Apr; 7(4):597-605. PMID: 7547687
Previous results from this laboratory demonstrated that the dominant influenza A epitope recognized by HLA-A2.1-restricted cytotoxic T lymphocytes (CTL) from HLA-A2.1 transgenic mice was the matrix protein 1 (M1) peptide...