C J Hatcher
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Explore the profile of C J Hatcher including associated specialties, affiliations and a list of published articles.
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8
Citations
187
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Recent Articles
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Hatcher C, Kim M, Basson C
Trends Cardiovasc Med
. 2001 Jun;
10(3):93-101.
PMID: 11428001
Molecular genetic analyses of human hereditary disorders that affect cardiac atrial structure and function have recently identified several genes that regulate atrial morphogenesis. Mutations of the TBX5, NKX2.5, EVC, and...
3.
Hatcher C, Kim M, Mah C, GOLDSTEIN M, Wong B, Mikawa T, et al.
Dev Biol
. 2001 Feb;
230(2):177-88.
PMID: 11161571
Mutations in human TBX5, a member of the T-box transcription factor gene family, cause congenital cardiac septation defects and isomerism in autosomal dominant Holt-Oram syndrome. To determine the cellular function...
4.
Hatcher C, GOLDSTEIN M, Mah C, Delia C, Basson C
Dev Dyn
. 2000 Sep;
219(1):90-5.
PMID: 10974675
Mutations in the TBX5 transcription factor gene cause human cardiac malformation in Holt-Oram syndrome. To identify and localize TBX5 during cardiac morphogenesis, we performed immunohistochemical studies of TBX5 protein cardiac...
5.
Casey M, Vaughan C, He J, Hatcher C, Winter J, Weremowicz S, et al.
J Clin Invest
. 2000 Sep;
106(5):R31-8.
PMID: 10974026
Cardiac myxomas are benign mesenchymal tumors that can present as components of the human autosomal dominant disorder Carney complex. Syndromic cardiac myxomas are associated with spotty pigmentation of the skin...
6.
Hatcher C, Godt R, Nosek T
Pflugers Arch
. 1999 Jul;
438(3):307-13.
PMID: 10398860
Ablation of the cardiac neural crest (CNCA) in embryonic chicks results in a high incidence of persistent truncus arteriosus, a congenital heart defect associated with decreased myocardial contractility. Using left...
7.
Conway S, Godt R, Hatcher C, Leatherbury L, Zolotouchnikov V, Brotto M, et al.
J Mol Cell Cardiol
. 1997 Nov;
29(10):2675-85.
PMID: 9344762
Around 85% of embryos homozygous for the splotch (Sp2H) allele (Sp2H/Sp2H), a Pax3 mutation, develop persistent truncus arteriosus (PTA), a defect related to the cardiac neural crest. These embryos die...
8.
Nosek T, Fogaca R, Hatcher C, Brotto M, Godt R
Am J Physiol
. 1997 Oct;
273(3 Pt 2):H1464-71.
PMID: 9321838
Cardiac neural crest ablation (CNCA) in the chick embryo at stages 8-10 results in reduced contractility of the heart that can be observed as early as stage 14. We found...